View Vol. 1 No. 2 (2010): Volume 1 Issue 2
Published: 2010-04-05

Original Articles

  • Development and validation of stability indicating HPLC method for the estimation of 5-Fluorouracil and related substances in topical formulation

    Sriguru Bandana (1), Nandha NP (2), Vairale AS (3), Sherikar AV (4), Nalamothu V (5)
    (1) Department of Dermatology, Analytical Research & Development, Dr.Reddy’s Laboratories, IPDO, Bachupally, Hyderabad- 500 072, India, India,
    (2) Department of Pharmacy & Biomedical Sciences, College of Pharmacy, University of South Carolina, Columbia, USA, United States,
    (3) Department of Dermatology, Analytical Research & Development, Dr.Reddy’s Laboratories, IPDO, Bachupally, Hyderabad- 500 072, India, India,
    (4) Department of Dermatology, Analytical Research & Development, Dr.Reddy’s Laboratories, IPDO, Bachupally, Hyderabad- 500 072, India, India,
    (5) Department of Dermatology, Analytical Research & Development, Dr.Reddy’s Laboratories, IPDO, Bachupally, Hyderabad- 500 072, India, India
    DOI record not available
    78-85
    Abstract Views : 44
    Download :14
  • N-Bromosuccinimide/fluorescein system for spectrophotometric determination of H2-receptor antagonists in their dosage forms

    Ibrahim A. Darwish (1), Samiha A. Hussein (2), Ashraf M. Mahmoud (3), Ahmed I. Hassan (4)
    (1) Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Kingdom of Saudi Arabia, Saudi Arabia,
    (2) Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt, Egypt,
    (3) Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt, Egypt,
    (4) Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Al-Azhar University, Assiut, 71524, Egypt, Egypt
    DOI record not available
    86-93
    Abstract Views : 34
    Download :10
  • Design, development and in vitro evaluation of Mesalamine tablets containing Pectin and Chitosan for colon-specific drug delivery

    Nirav V. Patel (1), Jayvadan K. Patel (2), Shreeraj H. Shah (3), Jagruti J Patel (4)
    (1) Anand Pharmacy College, Anand, Gujarat – 388 001, India, India,
    (2) Nootan Pharmacy College, Visnagar, Gujarat - 384 315, India, India,
    (3) L. J. Institute of Pharmacy, Ahmadabad, Gujarat – 382 210, India, India,
    (4) Kalol Institute of Pharmacy, Kalol, Gujarat -382721, India, India
    DOI record not available
    94-102
    Abstract Views : 56
    Download :25
  • Estimation of Valsartan and Nebivolol in pharmaceutical dosage forms by absorption ratio method

    Chaudhary Ankit B (1), Patel Rakesh K (2), Chaudhary Sunita A (3)
    (1) Saraswati Institute of Pharmaceutical science, Dhanap, Gandhinagar, Gujarat, India, India,
    (2) Shree S. K. Patel College of Pharmaceutical Education and Research, Ganapat University, Mehsana, Gujarat, India, India,
    (3) Saraswati Institute of Pharmaceutical science, Dhanap, Gandhinagar, Gujarat, India, India
    DOI record not available
    108-112
    Abstract Views : 22
    Download :48
  • Enhancement of dissolution of Fenofibrate by Solid dispersion Technique

    Tejas Patel (1), L. D. Patel (2), Timir Patel (3), Sunil Makwana (4), Tushar Patel (5)
    (1) Faculty of Pharmacy, Dharmsinh Desai University, Nadiad-387001, Gujarat, India, India,
    (2) C. U. Shah College of Pharmacy, Wadhawan, Gujarat, India, India,
    (3) Faculty of Pharmacy, Dharmsinh Desai University, Nadiad-387001, Gujarat, India, India,
    (4) Faculty of Pharmacy, Dharmsinh Desai University, Nadiad-387001, Gujarat, India, India,
    (5) Faculty of Pharmacy, Dharmsinh Desai University, Nadiad-387001, Gujarat, India, India
    DOI record not available
    127-132
    Abstract Views : 66
    Download :25
  • Eco-benign mediated versatile synthesis of newer quinazolin-4- (3H)-one clubbed isatin derivatives as potent antimicrobial agents

    Ilango K (1), Valentina P (2), Umarani N (3), Beena K.P. (4)
    (1) Department of Pharmaceutical Chemistry, College of Pharmacy, SRM University, Kattankulathur – 603203, Kancheepuram (Dt.), Tamil Nadu, India, India,
    (2) Department of Pharmaceutical Chemistry, College of Pharmacy, SRM University, Kattankulathur – 603203, Kancheepuram (Dt.), Tamil Nadu, India, India,
    (3) Department of Pharmaceutical Chemistry, College of Pharmacy, SRM University, Kattankulathur – 603203, Kancheepuram (Dt.), Tamil Nadu, India, India,
    (4) Department of Pharmaceutical Chemistry, College of Pharmacy, SRM University, Kattankulathur – 603203, Kancheepuram (Dt.), Tamil Nadu, India, India
    DOI record not available
    133-138
    Abstract Views : 29
    Download :11
  • Evidence based analysis of chemical method of induction of diabetes mellitus in experimental rats

    Etuk E.U. (1), Muhammed B.J. (2)
    (1) Department of Pharmacology, College of Health Sciences, Usmanu Danfodiyo University, Sokoto, Nigeria, Nigeria,
    (2) Department of Pharmacology, College of Health Sciences, Usmanu Danfodiyo University, Sokoto, Nigeria, Nigeria
    DOI record not available
    139-142
    Abstract Views : 32
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  • Synthesis and Evaluation of Anti-Depressant like Activity of Some Novel Thieno 1, 2, 3 – triazine 4 – ones

    Srinath R (1), Pinkal D. Vithlani (2), Saravanan J (3), Pravin S. Jagdale (4), Prashant Raghav (5), Aravind Shenoy (6)
    (1) Department of Pharmacology, P.E.S. College of Pharmacy, Bangalore, Karnataka, India, India,
    (2) Department of Pharmacology, P.E.S. College of Pharmacy, Bangalore, Karnataka, India, India,
    (3) Department of Pharmacology, P.E.S. College of Pharmacy, Bangalore, Karnataka, India, India,
    (4) Department of Pharmacology, P.E.S. College of Pharmacy, Bangalore, Karnataka, India, India,
    (5) Department of Pharmacology, P.E.S. College of Pharmacy, Bangalore, Karnataka, India, India,
    (6) Department of Pharmacology, P.E.S. College of Pharmacy, Bangalore, Karnataka, India, India
    DOI record not available
    143-150
    Abstract Views : 27
    Download :10
  • New Sensitive HPLC Method for Evaluation of the Pharmacokinetics of New Amantadine Prodrugs as Hepatic Delivery Systems to Enhance its Activity against HCV *

    Ibrahim A. Darwish (1), Tarek Aboul-Fadl (2), Nasr Y. Khalil (3), Ashraf M. Mahmoud (4), Abdul-Rahman M. Al-Obaid (5)
    (1) Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2475, Riyadh 11451, Kingdom of Saudi Arabia, Saudi Arabia,
    (2) Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2475, Riyadh 11451, Kingdom of Saudi Arabia, Saudi Arabia,
    (3) Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2475, Riyadh 11451, Kingdom of Saudi Arabia, Saudi Arabia,
    (4) Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2475, Riyadh 11451, Kingdom of Saudi Arabia, Saudi Arabia,
    (5) Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2475, Riyadh 11451, Kingdom of Saudi Arabia, Saudi Arabia
    DOI record not available
    151-157
    Abstract Views : 21
    Download :11
  • Effects of Pioglitazone, Glimepiride, Nobivolol, Valsartan and Hesperidine on Serum Diabetic Marker and Lipid Metabolizing Enzymes in Isoproterenol Induced Myocardial Infarction in Normal and Diabetic Rats

    Jagdish Kakadiya (1), Nehal Shah (2)
    (1) Pharmacology Department, Dharmaj Degree Pharmacy College, Petlad -Khambhat Road, Dharmaj, Anand-388430, Gujarat, India, India,
    (2) Pharmacology Department, Dharmaj Degree Pharmacy College, Petlad -Khambhat Road, Dharmaj, Anand-388430, Gujarat, India, India
    DOI record not available
    158-162
    Abstract Views : 28
    Download :18
  • Reverse phase HPLC method for the determination of Pravastatin in tablet dosage forms

    Delhi Raj N. (1), Kumaravel S. (2), Murugan R. (3), Sriman Narayanan S. (4), Vijayalakshmi R. (5)
    (1) Department of Pharmaceutical Analysis, Brown’s College of Pharmacy, Khammam, Telangana, India, India,
    (2) Department of Analytical Research Development, Micro Labs Limited, Bangalore, Karnataka, India, India,
    (3) Department of Analytical Chemistry, University of Madras, Chennai, Tamil Nadu, India, India,
    (4) Department of Analytical Chemistry, University of Madras, Chennai, Tamil Nadu, India, India,
    (5) Department of Pharmaceutical Analysis, Gautam College of Pharmacy, Bangalore, Karnataka, India, India
    DOI record not available
    187-189
    Abstract Views : 33
    Download :14
  • RP-HPLC method development and validation for estimation of Voglibose in bulk and tablet dosage forms

    Mallikarjuna Rao N. (1), Konda Ravi Kumar (2), Bagyalakshmi J. (3), Ravi T.K. (4), Ramakotaiah Mogili (5)
    (1) Department of Pharmaceutical Analysis, College of Pharmacy, Sri Ramakrishna Institute of Paramedical Sciences, New Siddapudur, Coimbatore, Tamilnadu, India, India,
    (2) Department of Pharmaceutical Chemistry, Siddhartha Institute of Pharmaceutical Sciences, JonnalaGadda, Narasaraopet, Guntur – 522601, Andhra Pradesh, India, India,
    (3) Department of Pharmaceutical Analysis, College of Pharmacy, Sri Ramakrishna Institute of Paramedical Sciences, New Siddapudur, Coimbatore, Tamilnadu, India, India,
    (4) Department of Pharmaceutical Analysis, College of Pharmacy, Sri Ramakrishna Institute of Paramedical Sciences, New Siddapudur, Coimbatore, Tamilnadu, India, India,
    (5) Department of Pharmaceutics, Don Bosco College of Pharmacy, Pulladigunta, Guntur (Dt) – 522 517 Andhra Pradesh, India, India
    DOI record not available
    190-194
    Abstract Views : 95
    Download :24
  • Protective Role of Pitcher of Nepenthes khasiana Hook against Dexamethazone Induced Hyperlipidemia and Insulin Resistance in Rats

    Dibyendu Shil (1), Mohanty J. P. (2), Trishna Das (3), Bhuyan N. R. (4), Uriah T. (5), Mohamed Saleem T. S. (6)
    (1) Girijananda Chowdhury Institute of Pharmaceutical Science, Department of Pharmacognosy, Azara, Guwahati, Assam, India, India,
    (2) Department of Pharmacognosy, Himalayan Pharmacy Institute, Majhitar, E.Sikkim 737136, India, India,
    (3) Girijananda Chowdhury Institute of Pharmaceutical Science, Department of Pharmacognosy, Azara, Guwahati, Assam, India, India,
    (4) Department of Pharmacognosy, Himalayan Pharmacy Institute, Majhitar, E.Sikkim 737136, India, India,
    (5) Department of Pharmacognosy, Himalayan Pharmacy Institute, Majhitar, E.Sikkim 737136, India, India,
    (6) Department of Pharmacology, Annamacharya College of Pharmacy, Rajampet 516126, Andhra Pradesh, India, India
    DOI record not available
    195-198
    Abstract Views : 39
    Download :21
  • Evaluation of antimicrobial activity of various bark extracts of bombax malabaricum

    Girija K. (1), Udaya chandrika P. (2), Lakshman K. (3), Pruthvi N. (4)
    (1) Department of Pharmacognosy, PES College of Pharmacy, Bangalore-560050, Karnataka, India, India,
    (2) Department of Pharmacognosy, PES College of Pharmacy, Bangalore-560050, Karnataka, India, India,
    (3) Department of Pharmacognosy, PES College of Pharmacy, Bangalore-560050, Karnataka, India, India,
    (4) Department of Pharmacognosy, PES College of Pharmacy, Bangalore-560050, Karnataka, India, India
    DOI record not available
    199-204
    Abstract Views : 33
    Download :23
  • Analytical method development and validation of different marketed Didanosine tablets by RP-HPLC

    Sathiya Sundar R. (1), Carolin Nimila I. (2), Ashok Kumar J. (3), Vijaya Kumar T.M. (4), Poovi G. (5), Sankar Anand R. (6)
    (1) Faculty of Pharmacy, PRIST University, Thanjavur-614904, Tamilnadu, India, India,
    (2) Faculty of Pharmacy, PRIST University, Thanjavur-614904, Tamilnadu, India, India,
    (3) Faculty of Pharmacy, PRIST University, Thanjavur-614904, Tamilnadu, India, India,
    (4) GIET School of Pharmacy, Rajamundary, Andhra Pradesh, India, India,
    (5) GIET School of Pharmacy, Rajamundary, Andhra Pradesh, India, India,
    (6) Jagans College of Pharmacy, Nellore, Andhra Pradesh, India, India
    DOI record not available
    205-208
    Abstract Views : 27
    Download :19
  • Validation of Spectrophotometric determination of Rabeprazole using Ferric Chloride (FeCl3)

    Madhuri D. (1), Chandrasekhar K. B. (2), Ramakotaiah M. (3), Somasekhar G. (4), Harinadhababa K. (5), Ravi Kumar K. (6)
    (1) Department of Chemistry, Jawaharlal Nehru Technological University, Anantapur, Andhra Pradesh, India, India,
    (2) Department of Chemistry, Jawaharlal Nehru Technological University, Anantapur, Andhra Pradesh, India, India,
    (3) Department of Chemistry, Jawaharlal Nehru Technological University, Anantapur, Andhra Pradesh, India, India,
    (4) Department of Pharmaceutical Sciences, Omer-Al-Muktar University, Libya, Libya,
    (5) Department of Pharmaceutical Sciences, Omer-Al-Muktar University, Libya, Libya,
    (6) Department of Chemistry, Jawaharlal Nehru Technological University, Anantapur, Andhra Pradesh, India, India
    DOI record not available
    209-211
    Abstract Views : 37
    Download :24
  • Preparation and evaluation of mucoadhesive microcapsules of Nimodipne

    Stephen Rathinaraj B. (1), Ch. Rajveer (2), Sudharshini S. (3), Kishore Reddy A. (4)
    (1) Department of Pharmaceutics, Vaagdevi College of Pharmacy, Warangal, Andhra Pradesh, India, India,
    (2) Department of Pharmaceutics, Vaagdevi College of Pharmacy, Warangal, Andhra Pradesh, India, India,
    (3) Department of Pharmaceutics, Vaagdevi College of Pharmacy, Warangal, Andhra Pradesh, India, India,
    (4) Department of Pharmaceutics, Vaagdevi College of Pharmacy, Warangal, Andhra Pradesh, India, India
    DOI record not available
    219-224
    Abstract Views : 21
    Download :16

Review Article

  • Excipients Updates for Orally Disintegrating Dosage Forms

    Sunita A. Chaudhary (1), Ankit B. Chaudharya (2), Tejal A. Mehta (3)
    (1) Saraswati Institute of Pharmaceutical Science, Dhanap, Gandhinagar, Gujarat, India, India,
    (2) Saraswati Institute of Pharmaceutical Science, Dhanap, Gandhinagar, Gujarat, India, India,
    (3) Institute of Pharmacy, Nirma University, Ahmedabad, Gujarat, India, India
    DOI record not available
    103-107
    Abstract Views : 28
    Download :82
  • Anti-Tubercular Activity of Isatin Derivatives

    Tarek Aboul-Fadl (1), Fayzah A. S. Bin-Jubair (2)
    (1) Department of Pharmaceutical Chemistry, King Saud University, Riyadh - 11451 Saudi Arabia, Saudi Arabia,
    (2) Department of Pharmaceutical Chemistry, King Saud University, Riyadh - 11451 Saudi Arabia, Saudi Arabia
    DOI record not available
    113-126
    Abstract Views : 43
    Download :13
  • Nanoparticle Formulation for Hydrophilic & Hydrophobic Drugs

    Vivek Kumar Gupta (1), Karar P.K. (2), Ramesh S. (3), Misra S.P. (4), Alok Gupta (5)
    (1) Sherwood College of Pharmacy, Barabanki, Utter Pradesh, India, India,
    (2) Doaba College of Pharmacy, Ghataur, Kharar, Mohali, Punjab, India, India,
    (3) Sri Padmavathi School of Pharmacy, Tirupati, Andhra Pradesh, India, India,
    (4) Institute of Pharmacy, Sitapur, Uttar Pradesh, India, India,
    (5) Sherwood College of Pharmacy, Barabanki, Utter Pradesh, India, India
    DOI record not available
    163-169
    Abstract Views : 53
    Download :22
  • Polymers in mucoadhesive buccal drug delivery system – A review

    Punitha S (1), Girish Y (2)
    (1) Faculty of Pharmacy, PRIST University, Thanjavur, Tamilnadu, India, India,
    (2) Faculty of Pharmacy, PRIST University, Thanjavur, Tamilnadu, India, India
    DOI record not available
    170-186
    Abstract Views : 63
    Download :33
  • Microsponge drug delivery: A Review

    Viral Shaha (1), Hitesh Jain (2), Jethva Krishna (3), Pramit Patel (4)
    (1) Department of Pharmaceutics, Sigma Institute of Pharmacy, Gujarat, India, India,
    (2) Department of Pharmaceutics, Sigma Institute of Pharmacy, Gujarat, India, India,
    (3) Department of Pharmaceutics, Sigma Institute of Pharmacy, Gujarat, India, India,
    (4) Department of Pharmacology, R.C. Patel Institute of Pharmaceutical Education and Research, Gujarat, India, India
    DOI record not available
    212-218
    Abstract Views : 121
    Download :77