https://ijrps.com/home <p align="justify"><strong>International Journal of Research in Pharmaceutical Sciences (IJRPS)</strong> ISSN: 0975-7538 sponsored by JK Welfare &amp; Pharmascope Foundation is established in the year 2009 with people from various avenues of the pharmacy profession. IJRPS is completely devoted to publications related to Pharmaceuticals and Health Sciences. IJRPS will be published quarterly. The journal publishes original research work that contributes significantly to further the scientific knowledge in Pharmaceutical and Health Sciences.</p> en-US ijrpseditor@gmail.com (Editor) ijrpseditor@gmail.com (Managing Editor) Wed, 17 Jul 2024 10:26:36 +0000 OJS 3.3.0.10 http://blogs.law.harvard.edu/tech/rss 60 https://ijrps.com/home/article/view/4679 Health professionals and consumers are increasingly urging food corporations to produce healthier options, leading to a rise in the popularity of gluten-free flours like millet, sweet potatoes, and mung bean flour. Nutraceutical muffins offer a novel approach by combining the enjoyment of a tasty snack with the health benefits of bioactive compounds. These muffins are formulated with ingredients such as mung bean flour, spinach powder, guava powder, jaggery, and ghee to provide dietary fiber, vitamins, minerals, and antioxidants. Gluten-free and suitable for diabetics, they also address health concerns such as energy enhancement, vitamin deficiency, constipation, and bone health. In conclusion, nutraceutical muffins present an exciting way to merge health and flavor, making functional ingredients easily accessible in daily diets. However, further research is needed to optimize their formulation and validate their health benefits. Bhatt Mehul K, Goswami Dhruvi, Rajgor Hiral, Patel Devanshi, Vora Jahanavee, Talaviya Priti, Shah Nehal Copyright (c) 2024 International Journal of Research in Pharmaceutical Sciences https://creativecommons.org/licenses/by-nc-nd/4.0 https://ijrps.com/home/article/view/4679 Wed, 17 Jul 2024 00:00:00 +0000 https://ijrps.com/home/article/view/4678 The herb Kalanchoe lanceolata, which is widely used in traditional medicine, has showed promise in treating a range of ailments. Despite its widespread usage in traditional medicine, the phytochemical contents of K. lanceolata are not well studied, particularly in terms of its potential involvement in diabetes management. In this study, the objective was to identify the phytochemical constituents of K. lanceolata and determine how they can help with diabetes management. The whole plant methanolic, ethyl acetate, and petroleum ether extracts were analysed with GC-MS to identify bioactive components. In this study, 63 compounds were identified, 27 of which possess bioactive properties. Acorenone B, columbin, phytol, astaxanthin, β-sitosterol, 2,4-di-tert-butylphenol, and caryophyllene oxide are significant compounds found to be present in K. lanceolata. In silico molecular docking studies predicted the antidiabetic and antibacterial properties of phytochemical compounds. These compounds show potential as antibacterial, antifungal and antidiabetic agents. This study stresses the significance of K. lanceolata bioactive components and sheds light on the therapeutic potential in diabetes control. Sravanthi Suram, Lali Lingfa, Baloji Gugulothu, Srinivas Ankanagari Copyright (c) 2024 International Journal of Research in Pharmaceutical Sciences https://creativecommons.org/licenses/by-nc-nd/4.0 https://ijrps.com/home/article/view/4678 Wed, 17 Jul 2024 00:00:00 +0000 https://ijrps.com/home/article/view/4681 Change control plays a role in cGMP, just as all aspects of quality management should continually strive for enhancement. It works with a prior mechanism that empowers designated personnel across fields to assess, as well as having permission to authorize proposing or doing modifications that would impact the status that was prevalidated for the process system, including facilities, systems, and equipment. Change management involves overseeing changes in staff, protocols, operations, and product standards. These changes can occur in areas such as manufacturing, quality control, quality assurance, engineering, research and development (R&D), and marketing. Depending on their significance, changes may be categorized as critical, major, or minor; they may also be classified as emergency, planned, or unplanned based on their nature. Effective change management encompasses the coordination of personnel resources along with protocols to ensure consistency in operations and product excellence. It is a component of GMP compliance, as regulatory bodies mandate companies to demonstrate proficiency in managing changes. The process entails initiating a change request, followed by evaluating its impact on the product before devising an action plan for implementation, ultimately culminating with the Change Control Board (CCB) making decisions regarding the proposed changes. Soaib Ahmed, Souvik Kundu, Rahul Patra, Jaydip Ray Copyright (c) 2024 International Journal of Research in Pharmaceutical Sciences https://creativecommons.org/licenses/by-nc-nd/4.0 https://ijrps.com/home/article/view/4681 Fri, 26 Jul 2024 00:00:00 +0000