Elucidation of pharmacognostic profiles and pharmacological activity of Tephrosia Purpurea

Saravana Kumar K. (1) , Chandra Sekhar K.B. (2) , Jayachandra Reddy P. (3) , Grace Rathnam (4) , Sankari E. (5) , Nagaveni P. (6)
(1) Seshachala College of Pharmacy, Tirupati Chennai Highway, Puttur, Chittoor Dist. – 517583, Andhra Pradesh, India, India ,
(2) Department of Chemistry, Jawaharlal Nehru Technological University Anantapur, Anantapur - 515 002, Andhra Pradesh, India, India ,
(3) Department of Pharmaceutical Analysis, Krishna Teja Pharmacy College, Tirupati, Chittoor District - 517 506, Andhra Pradesh, India, India ,
(4) Department of Pharmaceutics, C.L. Baid Metha College of Pharmacy, Jyothi Nagar, Old Mahabalipuram Road, Thorapakkam, Chennai - 600 096, Tamil Nadu, India, India ,
(5) Seshachala College of Pharmacy, Tirupati Chennai Highway, Puttur, Chittoor Dist. – 517583, Andhra Pradesh, India, India ,
(6) Seshachala College of Pharmacy, Tirupati Chennai Highway, Puttur, Chittoor Dist. – 517583, Andhra Pradesh, India, India

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Vol. 2 No. 4 (2011): Volume 2 Issue 4
Keywords:
    Pyrogens, Methanolic extract, Anti-Pyretic activity, Pyrexia, Brewer’s yeast
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Abstract

The Cause of fever in patients is mainly due to, when the body’s immune response is triggered by pyrogens (fever – producing substances). Pyrogens usually come from a source outside the body and in turn, stimulate the production of pyrogens inside the body. The plant is reported to contain coumarins, falvonoids, carotenoids, flavanones, iso-flavanones and quercetin. The plant has been reported to have anti-pyretic, anti-helmintic, hepato-protective, anti-ulcer, anti-inflammatory, antimicrobial properties. The methanolic extract of Tephrosia Purpurea leaves was investigated for its anti-pyretic activity. Anti-pyretic potential of methanolic extract was evaluated by Brewer’s yeast induced pyrexia test. The pyrexia in rats was reduced significantly (P<0.01) compared to that of control.

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Authors

Saravana Kumar K.
Seshachala College of Pharmacy, Tirupati Chennai Highway, Puttur, Chittoor Dist. – 517583, Andhra Pradesh, India
saravanakumar156@gmail.com (Primary Contact)
Chandra Sekhar K.B.
Department of Chemistry, Jawaharlal Nehru Technological University Anantapur, Anantapur - 515 002, Andhra Pradesh, India
Jayachandra Reddy P.
Department of Pharmaceutical Analysis, Krishna Teja Pharmacy College, Tirupati, Chittoor District - 517 506, Andhra Pradesh, India
Grace Rathnam
Department of Pharmaceutics, C.L. Baid Metha College of Pharmacy, Jyothi Nagar, Old Mahabalipuram Road, Thorapakkam, Chennai - 600 096, Tamil Nadu, India
Sankari E.
Seshachala College of Pharmacy, Tirupati Chennai Highway, Puttur, Chittoor Dist. – 517583, Andhra Pradesh, India
Nagaveni P.
Seshachala College of Pharmacy, Tirupati Chennai Highway, Puttur, Chittoor Dist. – 517583, Andhra Pradesh, India
Saravana Kumar K., Chandra Sekhar K.B., Jayachandra Reddy P., Grace Rathnam, Sankari E., & Nagaveni P. (2011). Elucidation of pharmacognostic profiles and pharmacological activity of Tephrosia Purpurea. International Journal of Research in Pharmaceutical Sciences, 2(4), 688–691. Retrieved from https://ijrps.com/home/article/view/3396
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