Elucidation of pharmacognostic profiles and pharmacological activity of Tephrosia Purpurea

Abstract

The Cause of fever in patients is mainly due to, when the body’s immune response is triggered by pyrogens (fever – producing substances). Pyrogens usually come from a source outside the body and in turn, stimulate the production of pyrogens inside the body. The plant is reported to contain coumarins, falvonoids, carotenoids, flavanones, iso-flavanones and quercetin. The plant has been reported to have anti-pyretic, anti-helmintic, hepato-protective, anti-ulcer, anti-inflammatory, antimicrobial properties. The methanolic extract of Tephrosia Purpurea leaves was investigated for its anti-pyretic activity. Anti-pyretic potential of methanolic extract was evaluated by Brewer’s yeast induced pyrexia test. The pyrexia in rats was reduced significantly (P<0.01) compared to that of control.