Evaluation of anti-bacterial, anti-fungal and sun protective property of butanolic extracts of peel of fruit of Musa paradisiaca

Madhuri D (1) , Nagarajan G (2) , Bhasker Babu N (3)
(1) Creative Educational Society’s College of Pharmacy, Kurnool - 518218, Andhra Pradesh, India, India ,
(2) Dr. K. V. Subba Reddy Institute of Pharmacy, Kurnool-518218, Andhra Pradesh, India, India ,
(3) Dr. K. V. Subba Reddy Institute of Pharmacy, Kurnool-518218, Andhra Pradesh, India, India

Abstract

The extract was obtained by using the peel of the ripe banana fruit (Musa paradisiaca). The alcohol extract was prepared by homogenization and allowing to react for at least 48-72 hrs by using normal butanol, butanol with acidic and basic conditions. The entire slurry was filtered. The butanolic extract of peel of Musa paradisiaca (BEPMP) was used and tested for antimicrobial activity and sun protective activity (in vitro). Also a BEPMP obtained by soxhlation using n-butanol for 3 hrs and the BEPMP was used for the anti-microbial activity and sun protective activity. Each BEPMP was evaporated to 2 ml and tested for antimicrobial and sun protective activity using suitable techniques. The BEPMP obtained by maceration and soxhlation methods were found to show antimicrobial and sun protective activity. The BEPMP was tested in a spectrophotometer as UVA (400-315nm) and UVB (315-280nm) effects are short lived and reversible, these effects include sunburn and tanning. The aim of the present investigation was to evaluate peel BEPMP with regard to UV absorption spectra in view of a possible anti solar agents. The BEPMP obtained by different methods showed λmax of 370nm with an optical density of 1.98 and 2.24 respectively which showed the antioxidant activity and photoprotective activity due to the presence of phenolics.

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Authors

Madhuri D
madhuri.pharma@rediffmail.com (Primary Contact)
Nagarajan G
Bhasker Babu N
Madhuri D, Nagarajan G, & Bhasker Babu N. (2018). Evaluation of anti-bacterial, anti-fungal and sun protective property of butanolic extracts of peel of fruit of Musa paradisiaca. International Journal of Research in Pharmaceutical Sciences, 9(2), 378–380. Retrieved from https://ijrps.com/home/article/view/4218

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