Overview of current technologies in ocuserts for the treatment of ophthalmic diseases

Sowjanya A.; Mallikarjuna Rao K.; Gnanaprakash K.; Divya A.; Vidyasagar N.; Gobinath M.

Sowjanya A. ⁽¹⁾ , Mallikarjuna Rao K. ⁽²⁾ , Gnanaprakash K. ⁽³⁾ , Divya A. ⁽⁴⁾ , Vidyasagar N. ⁽⁵⁾ , Gobinath M. ⁽⁶⁾

(1) Department of Pharmaceutics, Ratnam Institute of Pharmacy Pidathapolur, Nellore - 524346, Andhra Pradesh, India, India ,

(2) Department of Pharmaceutics, Ratnam Institute of Pharmacy Pidathapolur, Nellore - 524346, Andhra Pradesh, India, India ,

(3) Department of Pharmaceutics, Ratnam Institute of Pharmacy Pidathapolur, Nellore - 524346, Andhra Pradesh, India, India ,

(4) Department of Pharmaceutics, Ratnam Institute of Pharmacy Pidathapolur, Nellore - 524346, Andhra Pradesh, India, India ,

(5) Department of Pharmaceutics, Ratnam Institute of Pharmacy Pidathapolur, Nellore - 524346, Andhra Pradesh, India, India ,

(6) Department of Pharmaceutics, Ratnam Institute of Pharmacy Pidathapolur, Nellore - 524346, Andhra Pradesh, India, India

Issue
Vol. 3 No. 4 (2012): Volume 3 Issue 4

Keywords:

Ocuserts, kneading method, Glaucoma, cul-de-sac, film casting method, conjunctivitis, Keratitis

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Abstract

Ocular drug delivery is one of the most fascinating and challenging tasks facing the Pharmaceutical researchers. One of the major barriers of ocular medication is to obtain and maintain a therapeutic level at the site of action for prolonged period of time. The development of newer, more sensitive diagnostic techniques and therapeutic agents renders urgency to the development of maximum successful and advanced ocular drug delivery systems. The main objective of the present review was to describe different technologies used for the preparation of ocuserts and importance of ocuserts in the treatment of ophthalmic diseases. Different categories of drugs used for the treatment of ophthalmic diseases such as anti-viral, anti-biotics, anti-glaucoma, anti-bacterial and anti- fungal drugs. Methods involved in the preparation of ocuserts like solvent casting method, film casting and kneading method. Finally concluded that the present review gives the full description about ocular drug delivery system for the treatment of ophthalmic disease in effective manner.