Potential hypoglycemic & hypolipidemic effect of Morus Indica and Asystasia gangetica in alloxan induced diabetes mellitus

Abstract

The present research was made to investigate the potential hypoglycemic and hypolipidemic effect of Morus Indica and Asystasia gangetica in alloxan induced diabetes mellitus. Diabetes was induced by alloxan (150 mg/kg i.p) into rats. Ethanolic extract of leaves of Morus Indica and Asystasia gangetica was administered to alloxan induced diabetic rats. Glibenclamide used as a reference standard. Blood glucose, triglycerides, cholesterol, HDL-cholesterol, LDL-cholesterol and total proteins were estimated from the serum by using standard kits. All groups show significant increase in the level of biochemical parameters were decreased by administration of ethanolic extract of leaves of Morus Indica and Asystasia gangetica. From this study it has been concluded that the ethanolic extracts of leaves of Morus Indica and Asystasia gangetica having good hypoglycemic and hypolipidemic effect.