Cytological and histopathological studies on the effect of honey in experi mentally infected wounds in Wistar rats

Neeraja Rani Guruvu (1) , Bandaru Narasinga Rao (2) , Vijayaraghavan R (3) , Sukumar E (4) , Senthilkumar Sivanesan (5)
(1) Department of Pharmacology, SIMATS, GEMS, Srikakulam-532484, Andhra Pradesh, India, India ,
(2) Department of Microbiology, Gayatri Vidya Parishad Institute of Health Care and Medical Technology, Marikavalasa, Madhurawada, Visakhapatnam – 530048, Andhra Pradesh, India, India ,
(3) Department of Research, Saveetha Institute of medial and technical science, Thandalam, Chennai – 602105, Tamil Nadu, India, India ,
(4) Department of Research, Saveetha Institute of medial and technical science, Thandalam, Chennai – 602105, Tamil Nadu, India, India ,
(5) Department of Research, Saveetha Institute of medial and technical science, Thandalam, Chennai – 602105, Tamil Nadu, India, India

Abstract

Honey is used as food and home remedy in of India and other countries. Scientific studies have been carried out to support these properties of honey in this investigation, incision wounds of rats that were infected with three bacterial strains viz. Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa, have been treated with honey and evaluated for its effect on days 1, 3, 6, 9 and 12 post-operatively with the help of smears and biopsies collected from lesions. Cytological and histopathological investigations of infected wounds conformed significant healing property of honey in and reduction in size.

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Authors

Neeraja Rani Guruvu
neerajarao.nakka@gmail.com (Primary Contact)
Bandaru Narasinga Rao
Vijayaraghavan R
Sukumar E
Senthilkumar Sivanesan
Neeraja Rani Guruvu, Bandaru Narasinga Rao, Vijayaraghavan R, Sukumar E, & Senthilkumar Sivanesan. (2019). Cytological and histopathological studies on the effect of honey in experi mentally infected wounds in Wistar rats. International Journal of Research in Pharmaceutical Sciences, 10(2), 1190–1195. Retrieved from https://ijrps.com/home/article/view/3790

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