Study of in-vitro antioxidant activity of various extracts of aerial parts of Olax scandens

Abstract

Olax scandensRoxb. (family Olacaceae) Available in  throughout tropical India. The current study, aerial parts of different concentrates of Olax scandenswas evaluated for its in-vitro  antioxidant potential by Diphenylpicrylhydrazyl activity, superoxide scavenging activity, iron chelating activity taking ascorbate, quercetin & Ethylenediamine tetraacetate as the standard correspondingly. An IC₅₀ value was originated that methanolic concentrates of Olax scandensis more efficient in Diphenylpicrylhydrazyl radical, superoxide radical activity, Iron chelating capacity compared EA & PE concentrates. The methanolic concentrates of Olax scandens & ascorbate exhibited antioxidant potential possessing IC₅₀ 226µg/ml & 66µg/ml (DPPH). 185µg/ml & 60µg/ml (Superoxide) , 287µg/ml & 65µg/ml (iron-chelating Activity) respectively. Invitro antioxidant studies obviously show methanolic concentrates of Olax scandens have better antioxidant activity. These results indicate that aerial parts of methanolic concentrates Olax scandens could serve as a natural antioxidant, which may be useful in preventing free radical-induced diseases.