Understanding the pathogen evolution and transmission prevention measures: Recent findings on molecular interventions towards COVID-19 therapeutics via hints from the past

Vinusha H M (1) , Chandan Shivamallu (2) , Shashanka K Prasad (3) , Muneera Begum (4) , Gopinath S M (5) , Chandrashekar Srinivasa (6) , Latha K Chennabasappa (7) , Navya Shree B (8) , Shiva Prasad Kollur (9) , Veena Malligere Ankegowda (10) , Balasubramanian S (11)
(1) Department of Chemistry, JSS Science and Technology University, Mysuru, Karnataka–570006, India, India ,
(2) Department of Biotechnology and Bioinformatics, JSS Academy of Higher Education & Research, Mysuru–570015, Karnataka, India, India ,
(3) Department of Biotechnology and Bioinformatics, JSS Academy of Higher Education & Research, Mysuru–570015, Karnataka, India, India ,
(4) Department of Chemistry, JSS Science and Technology University, Mysuru, Karnataka–570006, India, India ,
(5) Department of Biotechnology, Davangere University, Shivagangotri, Davanagere–577007, Karnataka, India, India ,
(6) Department of Chemistry, Sarada Vilas College, Mysuru, Karnataka–570004, India, India ,
(7) Department of Education, University Grants Commission, Bangalore, Karnataka-56009, India, India ,
(8) Department of Zoology, JSS College of Arts, Commerce and Science (Autonomous), Mysuru, Karnataka–570015, India, India ,
(9) Department of Sciences, Amrita School of Arts and Sciences, Mysuru, Karnataka–570026, India, India ,
(10) Department of Chemistry, Bangalore Institute of Technology, K.R. Road, Bangalore-560004, Karnataka, India, India ,
(11) Department of Research, JSS Academy of Higher Education & Research, Mysuru-570015, Karnataka, India, India

Abstract

The novel coronavirus pandemic has spread over in 150 countries as of March 2020. Approximately 900,000 people have been infected so far (WHO).  Preventive measures are been taken globally to contain the rapid spread of virus. Compared to 2002 SARS epidemic, COVID-19 is apparently less lethal but far more contagious as it spreads more easily among individuals. This review highlights ongoing progress in figuring out the structure of major proteins designing vaccines and therapeutics to combat COVID-19 while also concentrating on developing preventive steps to avoid the emerging infection of viruses.

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Authors

Vinusha H M
Chandan Shivamallu
Shashanka K Prasad
Muneera Begum
Gopinath S M
Chandrashekar Srinivasa
Latha K Chennabasappa
Navya Shree B
Shiva Prasad Kollur
shivachemist@gmail.com (Primary Contact)
Veena Malligere Ankegowda
Balasubramanian S
Vinusha H M, Chandan Shivamallu, Shashanka K Prasad, Muneera Begum, Gopinath S M, Chandrashekar Srinivasa, Latha K Chennabasappa, Navya Shree B, Shiva Prasad Kollur, Veena Malligere Ankegowda, & Balasubramanian S. (2020). Understanding the pathogen evolution and transmission prevention measures: Recent findings on molecular interventions towards COVID-19 therapeutics via hints from the past. International Journal of Research in Pharmaceutical Sciences, 11((SPL 1), 442–451. Retrieved from https://ijrps.com/home/article/view/1522

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