Anti-hyperlipidemic Activity of Lannea coramandelica Leaf Extract Against Experimentally Induced Hyperlipidemia in Rats

Abstract

Hyperlipidemia and hypercholesterolemia are interrelated terms and the same course of disorders which raise the serum levels of cholesterol and triglycerides. Herbs are used for treating diseases and used in the traditional systems of medicines like Ayurveda. As science is evolving, research to prove the pharmacological activity of the herbs and establishing scientific proof is also important. Lannea coramandelica is a native plant for tropical countries like India. It is considered one of the lifesavers of the area with abundant polyphenols, flavonoids, gums and other chemical constituents. Most of the antioxidant chemical components like flavonoids are potent in treating and lowering lipids in the body and reduces the oxidative stress in the human body to process fats. Lannea coramandelica has been proven to have vast amounts of flavonoids and antioxidant principles. Current research has been designed to confirm the hyperlipidemia controlling property of Lannea coramandelica extracts. The Lannea coramandelica extract showed a better hyperlipidemic activity at a dose of 500mg/kg in both the events.