Therapeutic application of Resveratrol in human diseases

Abstract

Resveratrol (3,4,5-trihydroxystilbene) is a member of natural and plant-derived chemicals, which is known as polyphenols and it is getting more consideration because of its various health assistances. Largely in the case of neurological problems, cardiovascular disease, antiviral, cancer, antiaging. Although in the past few years, it has been shown that the families of enzymes Sirtuins, particularly situin1 (SIRT1), have an antiaging action. Thus, the natural compound resveratrol shows a very strong activation of SIRT1 and also shows antioxidant properties. The antioxidant effect mainly elicited by the inhibition of important pathways like the NF-ĸβ pathway. This review highlights the antiviral mechanism of resveratrol in human and animal viral infections. And also, information about cancer-related like colorectum cancer, skin cancer and lung cancer are also mentioned. Resveratrol also gives additional cardioprotective and vasoprotective properties, which include antiatherosclerotic action. Overall observation shows that resveratrol has a high therapeutic potential in the treatment of cardiovascular disease, anti-aging, antiviral and in the treatment of cancer.