Assessment of renal damage in hypothyroidism cases

Abstract

Hypothyroidism is a common disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormone. The kidney plays a role in the clearance of iodine, TSH, and thyrotropin-releasing hormone. Thyroid hormones influence the renal development, kidney structure, GFR, sodium, and water homeostasis. It also influences the function of transport systems along the nephron. So, there is a strong correlation between thyroid hormonal status and kidney function. 30 hypothyroidism patients and 30 healthy individuals were used from the OP of Saveetha Dental College. Serum samples were analyzed for the renal status by using a kit method in autoanalyzer. There is a significant increase in serum urea levels (p<0.05) and serum creatinine levels (p<0.05) in hypothyroidism patients. This is due to the thyroid hormones influence renal function. In our study, we observed that there is a strong correlation between thyroid hormones and renal damage, it that changes in thyroid profile can damage the renal system.