Association Between Insulin Resistance and Inflammation in Obese Individuals

Abstract

Obesity is a very common condition we can see in most of the people living in developing countries. Most obese cases are due to their lifestyle only. Obesity will affect other metabolisms and causes metabolic disorders like diabetes, renal damage and cardiovascular problems. 30 obese patients and 30 healthy individuals from the OP of Saveetha Dental College. Serum samples were estimated the FBS by GOD-POD Method, CRP by Turbilatex Method using ERBA CHEM 5 plus analyzer. Insulin level by ELISA method using RO- BONIK ELISA READER. There is a remarkable increase in FBS (p<0.005), Insulin (p<0.005), Insulin resistance (p<0.005) and highly remarkable increase in C reactive protein (p<0.001) in obese people compared to controls. Our results show that the increase in insulin resistance, insulin, sugar and inflammation states there is a potential risk of diabetes, renal damage and other metabolic abnormalities due to the obese condition.