Phytoconstituents and biological screening of aqueous extracts of Phyla nodiflora Linn.

Abstract

The aqueous extracts of dried roots and leaf, stem and flower parts of Phyla nodiflora Linn were subject for the preliminary Phytoconstituents analysis and ascertained that the plant possesses Glycosides, alkaloids, carbohydrates, proteins and amino acids, flavanoids, saponins, phytosterols and Terpenoids. Analgesic activities of the aqueous plant extracts of Phyla nodiflora Linn were assessed using acetic acid developed writhing peripheral analgesic method and hot plate central analgesic method in the mice. Both of the extracts showed significant peripheral and central analgesic activity. But the aerial parts of the extracts have shown more analgesic activity than root of the plant. The crude plant extracts and their solvent soluble fractions were subjected to antibacterial evaluation against four different bacteria Escherichia coli, Bacillus subtilis, Staphylococcus aureus and Pseudomonas aeruginosa. The result of anti bacterial screening revealed that aqueous extract failed to inhibit Escherichia coli, Bacillus subtilis, Staphylococcus aureus and Pseudomonas aeruginosa.