Assessment of Serum Vitamin D, Folic acid and Vitamin B12 in Congenital Heart Disease Patients in a Teritary Hospital
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Congenital heart disease, Vitamin D3, Vitamin B12, Malnutrition
Abstract
Congenital heart disease patient suffers from malnutrition irrespective of the types of cardiac defects. These children are often admitted in hospitals owing to congenital heart defects. Corrective catherization, proper nutritional intake and counselling can improve the malnutrition. To assess the vitamin status in children with congenital heart disease patients admitted in paediatric general ward of tertiary hospital. The study was a prospective observational study, a total of 100 patients were evaluated for their nutritional deficiency such as serum vitamin D3, folic acid and Vitamin B12 by employing ELISA KITS. The study observed a significant levels of vitamin D3 and folic acid depletion in congenital heart disease patients. There was no severe depletion of vitamin B12 in the current study. The study had made an insight into the malnutrition status of congenital heart disease patients and recommends consumption of micronutrients in congenital heart defect patients.
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References
Arodiwe, I., Chinawa, J., Ukoha, M., Ujunwa, F., Adiele, K., Onukwuli, V., Obidike, E., Eze, J. 2015. Nutritional status of children with congenital heart disease (CHD) attending university of Nigeria teaching hospital ituku – ozalla, Enugu. Pakistan Journal of Medical Sciences, 31(5):1140–1145.
Botto, L. D., Mulinare, J., Erickson, J. D. 2000. Occurrence of Congenital Heart Defects in Relation to Maternal Multivitamin Use. American Journal of Epidemiology, 151(9):878–884.
Daniel, W. W. 1999. Biostatistics: A Foundation for Analysis in the Health Sciences. 7th edition. New York: John Wiley & Sons.
Elizabeth, K. E., Praveen, S. L., Preethi, N. R., Jissa, V. T., Pillai, M. R. 2017. Folate, vitamin B12, homocysteine and polymorphisms in folate metabolizing genes in children with congenital heart disease and their mothers. European Journal of Clinical Nutrition, 71(12):1437–1441.
Looker, A. C., Pfeiffer, C. M., Lacher, D. A., Schleicher, R. L., Picciano, M. F., Yetley, E. A. 1988. Serum 25-hydroxyvitamin D status of the US population. The American Journal of Clinical Nutrition, 88(6):1519–1527.
Mcnally, J. D., Menon, K. 2013. Vitamin D deficiency in surgical congenital heart disease: prevalence and relevance. Translational pediatrics, 2(3):99– 111.
McNally, J. D., Menon, K., Chakraborty, P., Fisher, L., Williams, K. A., Al-Dirbashi, O. Y., Girolamo, T., Maharajh, G., Doherty, D. R. 2013. Impact of Anesthesia and Surgery for Congenital Heart Disease on the Vitamin D Status of Infants and Children. Anesthesiology, 119(1):71–80.
Meshram, R. M., Gajimwar, V. S. 2018. Prevalence, profile, and pattern of congenital heart disease in Central India: A prospective, observational study. Nigerian Journal of Cardiology, 15(1):45–49.
Noori, N. M., Moghadam, M. N., Teimouri, A., Pakravan, A., Boryri, T. 2018. 25-hydroxy Vitamin D Serum levels in Congenital Heart Disease (CHD) Children Compared to Controls. International Journal of Pediatrics, 6(8):8129–8138.
Rook, G. D., Lopez, R., Shimizu, N., Cooperman, J. M. 1973. Folic acid deficiency in infants and children with heart disease. Heart, 35(1):87–92.
Saxena, A. 2018. Congenital Heart Disease in India: A Status Report. Indian Pediatrics, 55(12):1075– 1082.
Varan, B., Tokel, K., Yilmaz, G. 1999. Malnutrition and growth failure in cyanotic and acyanotic congenital heart disease with and without pulmonary hypertension. Archives of Disease in Childhood, 81(1):49–52.
Zahr, R. A., Faustino, E. V. S., Carpenter, T., Kirshbom, P., Hall, E. K., Fahey, J. T., Kandil, S. B. 2017. Vitamin D Status After Cardiopulmonary Bypass in Children With Congenital Heart Disease. Journal of Intensive Care Medicine, 32(8):508–513.
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