Pharmacognostical Standardisation of Ailanthus Excelsa Leaves and Randia Dumetorum Fruit Along with Antioxidant Activity and Free Radical Scavenging Capacity of Its Fractions

Abstract

The world is observing an unprecedented development in the usage of herbal product at national as well as international levels. This requires the improvement of current and aimed standards for estimating the quality, safety and efficacy of these drugs. The leaves of Ailanthus excelsa and the fruits of Randia Dumetorum are medicinal plants that are used for many diseases around the world. We then collected the flavonoids and saponin fraction extracted from the leaves of Ailanthus excelsa and the fruits of Randia dumetorum. To determine the reliability, quality and purity of these particles, we provide a crucial pharmacological profile along with the antioxidant activity. Pharmacological studies, such as morphological, physicochemical, TLC, and phytochemical analysis of all fractions containing total phenol and flavonoids, were performed according to specific methods. DPPH tests estimated the antioxidant action of all fractions, Hydrogen peroxide scavenging assay, and reducing power assay method. Previous phytochemical studies discovered the occurrence of saponins, flavonoids, tannins, and especially phenolic chemicals. All fractions have antioxidant effects, depending on the existence of a phenolic compound. The above parameters are vital to establishing pharmacological rules for the authentication of Ailanthus excelsa leaves and Randia Dumetorum fruits.