Formulation and Evaluation of Innovative Anti-septic Solution For Wound healing

Abstract

Wound healing is a complex process in which the skin and their tissues are undergone self repairing after injury. The wound healing is not only complex but also fragile, and also susceptible to interruption or failure leading to the formulation of non healing chronic wounds, Tissue repair is a simple linear process in which the growth factor cause the proliferation which eventually leads to the skin healing process.  Currently in market there is no antiseptic spray solution is available for wound healing or retention process. The objective of current work is to formulate and optimize and evaluate a innovative wound healing solution. Silver sulfadiazine (0.5%) was optimized and finalized the concentration of excipients to make a prototype formulation. The batches were prepared under room temperature and it contains ingredients like 3% of PVP k30 which is used as thickening agent and stabilizing agent and it enhances retentivity property, 5% preservatives, 0.05% rosemary oil is used as a flavour, 0.05% brilliant blue was used as a colouring agent. Evaluation studies such as Appearance, Retentivity, Sensorial analysis was done. Silver sulfadiazine content was determined on the given stability condition and content found to be within specification.