Spectrophotometric estimation of Nifidipine by using various solvents

Alagar Raja M (1) , Selva Kumar D (2) , Muthu Kumar S (3) , Purnima Tripathi (4) , Amuthadevi C (5)
(1) Department of Pharmaceutical Analysis, Kamla Nehru Institute of Management & Technology, Faculty of Pharmacy, Faridipur, Sultanpur, Uttar Pradesh, India, India ,
(2) Arya Vaidhya Nilayam, Madurai, Tamil Nadu, India, India ,
(3) Department of Pharmaceutical Analysis, Kamla Nehru Institute of Management & Technology, Faculty of Pharmacy, Faridipur, Sultanpur, Uttar Pradesh, India, India ,
(4) Department of Pharmaceutical Analysis, Kamla Nehru Institute of Management & Technology, Faculty of Pharmacy, Faridipur, Sultanpur, Uttar Pradesh, India, India ,
(5) Ultra College of Pharmacy, Madurai, Tamil Nadu, India, India

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Vol. 1 No. 1 (2010): Volume 1 Issue 1
Keywords:
    Nifidipine, Dimethyl Formamide, Glacial Acetic Acid
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Abstract

A Simple and sensitive spectrophotometric method has been developed for the estimation of nifedipine in bulk and tablet formulation. The drug was determined by using various solvents like aqueous, organic and inorganic, which is determined spectrophotometrically at 281nm. The percentage recovery study of the drug for the proposed method range from 98-102% indicating no interference of the tablet excipients by using various solvents. The result obtained for percentage purity of nifidipine was dimethyl formamide and glacial acetic acid was only the solvents indicating the limit of recovery studies.

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Authors

Alagar Raja M
Department of Pharmaceutical Analysis, Kamla Nehru Institute of Management & Technology, Faculty of Pharmacy, Faridipur, Sultanpur, Uttar Pradesh, India
rajampharman_1982@yahoo.co.in (Primary Contact)
Selva Kumar D
Arya Vaidhya Nilayam, Madurai, Tamil Nadu, India
Muthu Kumar S
Department of Pharmaceutical Analysis, Kamla Nehru Institute of Management & Technology, Faculty of Pharmacy, Faridipur, Sultanpur, Uttar Pradesh, India
Purnima Tripathi
Department of Pharmaceutical Analysis, Kamla Nehru Institute of Management & Technology, Faculty of Pharmacy, Faridipur, Sultanpur, Uttar Pradesh, India
Amuthadevi C
Ultra College of Pharmacy, Madurai, Tamil Nadu, India
Alagar Raja M, Selva Kumar D, Muthu Kumar S, Purnima Tripathi, & Amuthadevi C. (2010). Spectrophotometric estimation of Nifidipine by using various solvents. International Journal of Research in Pharmaceutical Sciences, 1(1), 20–23. Retrieved from https://ijrps.com/home/article/view/2014
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