Extracts of Ficusgibboseblame and its potentiating effect for type II diabetes in rats

Abstract

Hydroalcoholic extract of Greeneries and stalkbark of Ficusgibbosa Blume  is evaluated for their potentiating action in Streptozotocin – Nicotinamide encouraged type 2 diabetes in Sprague Dawley rats. The excerpts are managed at the amount of 100, 250 and 500 mg/kg body weight along with sub operative dose (2.5 mg/kg body weight) of the standard antidiabetic drug (Glibenclamide) for a period of 5 weeks. The test extracts potentiated the antidiabetic activity of standard drug by significantly dropping the raised blood glucose levels and the effect was almost comparable with solitary efficacy of therapeutic dose (5 mg/kg body weight) of typical drug Glibenclamide during 5th week of the study. Its abandons have deviated, on the other hand, orchestrated and more gibbose in those end. The juice of the bark furthermore abandons from claiming color fig alternately bumped fig plant is utilized to grinding those pills furthermore settling on A decoction in toxicology. Plant appeases diminished Kapha, pitta, skin diseases, ulcers, hepatopathy, diabetes, ulcerative stomatitis, leucorrhoea and gynaecological issues. Male Sprague Dawley Rats abstainedinstantare vaccinated intraperitoneally with result about Nicotinamide at a dosage of 195 mg /kg body weight. 15 minutes after same animals are vaccinated for the newly readied result from claiming Streptozotocin (STZ) In measurement about (65 mg/kg physique weight) intraperitoneally. The animals are permitted to drink 1% glucose result instant will succeed the pill prompted hypoglycaemia.