Associations of Polymorphic Markers Aluins/Deli>D Ace T-786C Gene Enos3 in Diabetic Nefropate Progressing for Type 2 Diabetes Mellitus

Ozimboy O Jabbarov (1) , Botir T Daminov (2) , Kodirjon T Boboev (3) , Laylo D Tursunova (4) , Maxsuma X Tashpulatova (5) , Lola I Maksudova (6)
(1) Department of faculty and hospital therapy No.2, Farabi 2, Tashkent - 100109, Uzbekistan, Uzbekistan ,
(2) Department of Propaedeutics of Internal Diseases, Hospital and Faculty Therapy, Doctor of medicine, Bagishamal str., 223. Yunusabad region, Tashkent city - 100140, Uzbekistan, Uzbekistan ,
(3) Head of the Laboratory of Medical Genetics, Doctor of Medicine, Medical Care Department 138 Usman Nasyr street, Tashkent city - 100059, Uzbekistan, Uzbekistan ,
(4) Department of faculty and hospital therapy No.2, Farabi 2, Tashkent - 100109, Uzbekistan, Uzbekistan ,
(5) Department of faculty and hospital therapy No.2, Farabi 2, Tashkent - 100109, Uzbekistan, Uzbekistan ,
(6) Department of children’s infections, Bagishamal str., 223. Yunusabad region, Tashkent city - 100140, Uzbekistan, Uzbekistan

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Vol. 11 No. 4 (2020): Volume 11 Issue 4
Keywords:
    Diabetic Nephropathy, Type 2 Diabetes, ENOS3, Chronic Kidney Disease
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Abstract

In the current study, the development of diabetic nephropathy identified the relationship between the polymeric marker of AC genes and the NS3 gene. One hundred twenty-nine patients with type 2 diabetes were tried. Patients in the principle gathering: 65 people with diabetes nephropathy preserved kidney function (33 patients), and kidney function weakness (32 patients), 64 patients with Diabetes were enduring more than 10-20 years, diabetic nephropathy preserved the chain of genotyping polymers carries out kidney function (31 patients). The study showed a link between eNOS3 genes in the development of diabetic nephropathy in Type 2 diabetes patients, supported by the ACE gene.

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Authors

Ozimboy O Jabbarov
Department of faculty and hospital therapy No.2, Farabi 2, Tashkent - 100109, Uzbekistan
doctor.azim.jabborov@gmail.com (Primary Contact)
Botir T Daminov
Department of Propaedeutics of Internal Diseases, Hospital and Faculty Therapy, Doctor of medicine, Bagishamal str., 223. Yunusabad region, Tashkent city - 100140, Uzbekistan
Kodirjon T Boboev
Head of the Laboratory of Medical Genetics, Doctor of Medicine, Medical Care Department 138 Usman Nasyr street, Tashkent city - 100059, Uzbekistan
Laylo D Tursunova
Department of faculty and hospital therapy No.2, Farabi 2, Tashkent - 100109, Uzbekistan
Maxsuma X Tashpulatova
Department of faculty and hospital therapy No.2, Farabi 2, Tashkent - 100109, Uzbekistan
Lola I Maksudova
Department of children’s infections, Bagishamal str., 223. Yunusabad region, Tashkent city - 100140, Uzbekistan
Ozimboy O Jabbarov, Botir T Daminov, Kodirjon T Boboev, Laylo D Tursunova, Maxsuma X Tashpulatova, & Lola I Maksudova. (2020). Associations of Polymorphic Markers Aluins/Deli>D Ace T-786C Gene Enos3 in Diabetic Nefropate Progressing for Type 2 Diabetes Mellitus. International Journal of Research in Pharmaceutical Sciences, 11(4), 6028–6032. Retrieved from https://ijrps.com/home/article/view/1311
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