Enhanced Antibacterial Activity of Silver Nanoparticles Synthesised Using Symplocos Racemosa

Nirubama K (1) , Rajeshkumar S (2)
(1) Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Science, P H Road, Chennai - 77, TamilNadu, India, India ,
(2) Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Science, P H Road, Chennai - 77, TamilNadu, India, India

Abstract

The green synthesis methods for the nanoparticles are economically feasible. It does not require any adverse effect causing agents such as usage of temperatures, toxic chemicals, energy, high pressure in the scientific and medical applications. Oral pathogens such as Streptococcus mutans and Lactobacillus sp is the major causes for many oral diseases. The different types of antibiotics are used for the controlling of many oral diseases. In this tudy we enhance the activity of nanoparticles by adding antibiotics to control the oral pathogen growth in invitro. The silver nanoparticles are prepared from Symplocos racemosa plant extract. To study and compare about the enhanced antibacterial activity of silver nanoparticles synthesised using Symplocoa racemosa. The plant extract was prepared by using double distilled water. The microorganisms such as Streptococcus mutans, and Lactobacillus sp were chosen and cultured in respective culture media. The silver nanoparticles synthesised is introduced into cultured petri plates to observe the changes. The zone of inhibition of the growth of microorganisms was studied. The effect of the prepared silver nanoparticles is compared using effect with the normal antibiotics. As a result, it is evident that there is an increase in zone of inhibition comparing the normal antibiotic effect. Thus it can used as drug of the choice in future.

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Authors

Nirubama K
Rajeshkumar S
ssrajeshkumar@hotmail.com (Primary Contact)
Nirubama K, & Rajeshkumar S. (2020). Enhanced Antibacterial Activity of Silver Nanoparticles Synthesised Using Symplocos Racemosa. International Journal of Research in Pharmaceutical Sciences, 11(3), 4120–4125. Retrieved from https://ijrps.com/home/article/view/1002

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