Formulation and evaluation of Itraconazole granules

Authors

  • Raj Kapoor B Dayananda Sagar College of Pharmacy, Bangalore, Karnataka, India
  • Subbarao G V Spansules Formulations, R & D Department, Hyderabad, Telangana, India

Abstract

The aim of present study is preparation and evaluation of itraconazole granules. Poorly water soluble drugs like itraconazole are chosen for the present study. According to the BCS classification, Itraconazole belongs to class-II category (highly permeable and low soluble drug). Itraconazole is a weak basic drug (pK a=3. 7) having partition coefficient value of 8.1. Itraconazole is used for the treatment of fungal infections. In this study, The Parameters such as Sieve analysis, Rheological parameters, In vitro dissolution studies, Accelerated stability studies and the Test formulation was compared with marketed formulation are evaluated.

Keywords:

Itraconazole, Granules, In vitro dissolution, Accelerated stability studies

Downloads

Download data is not yet available.

Downloads

Published

2011-12-20

How to Cite

Raj Kapoor B, & Subbarao G V. (2011). Formulation and evaluation of Itraconazole granules. International Journal of Research in Pharmaceutical Sciences, 2(4), 698–701. Retrieved from https://ijrps.com/index.php/home/article/view/3401

Issue

Vol. 2 No. 4 (2011): Volume 2 Issue 4

Section

Original Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.