Efficiency of probiotics use in treatment of calves

Nikolay V. Melnik (1) , Vladimir I. Eremets (2) , Larisa A. Neminuschaya (3) , Valentina I. Klyukina (4) , Svetlana A. Gryn (5) , Evgenia V. Markova (6) , Irina N. Matveeva (7) , Sergey Yu. Smolentsev (8)
(1) All-Russian Scientific Research and Technological Institute of Biological Industry, Moscow region, 141142, Russia, Russian Federation ,
(2) All-Russian Scientific Research and Technological Institute of Biological Industry, Moscow region, 141142, Russia, Russian Federation ,
(3) All-Russian Scientific Research and Technological Institute of Biological Industry, Moscow region, 141142, Russia, Russian Federation ,
(4) All-Russian Scientific Research and Technological Institute of Biological Industry, Moscow region, 141142, Russia, Russian Federation ,
(5) All-Russian Scientific Research and Technological Institute of Biological Industry, Moscow region, 141142, Russia, Russian Federation ,
(6) All-Russian Scientific Research and Technological Institute of Biological Industry, Moscow region, 141142, Russia, Russian Federation ,
(7) All-Russian Scientific Research and Technological Institute of Biological Industry, Moscow region, 141142, Russia, Russian Federation ,
(8) Mari State University, Lenin Square 1, Yoshkar-Ola city, 424000, Russia, Russian Federation

Abstract

The comprehensive approach to solving the issue of the animal raising intensification, the integrated part of which is herd breeding, animal yield preservation and its development provision, conditioned the enhancement of the research works aimed at further investigation of young stock diseases, features of their digestion development, search of efficient preventive and treatment measures, feeds and feed additives for simulating animal growth and development. The main objective of this study was the exploration of comparative therapeutic efficiency of the use of Lactusan probiotic in treatment of calves, in acute digestive disturbances in the complex of conventional treatments. The experiment was carried out in the conditions of Danilovsky Complex of Semenovsky Stud Farm CJSC of Medvedev District in Mari El Republic in calves aged 2-4 days with clinical signs of digestive organs dysfunction. 3 experimental groups of calves were formed observing the principles of analogues. Calves of the first and the second experimental groups, in addition to the treatment regimen adopted at the farm, were given Lactusan probiotic with colostral milk or milk at the rate of 6 grams and 4 grams, respectively per one calf once a day. Haemotological and biochemical analysis was carried out in all experimental calves at the beginning of the experiment and 5, 10 and 15 days after the treatment start. The experience demonstrated that Lactusan has a normalizing effect on protein, carbohydrate, mineral metabolisms, and pH balance. The positive effect of this drug on animals is conditioned by the probiotic effect of lactulose -  it selectively stimulates the growth of useful intestinal normal flora by inhibiting pathogenic flora of colon.

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Authors

Nikolay V. Melnik
Vladimir I. Eremets
Larisa A. Neminuschaya
Valentina I. Klyukina
Svetlana A. Gryn
Evgenia V. Markova
Irina N. Matveeva
Sergey Yu. Smolentsev
Smolentsev82@mail.ru (Primary Contact)
Nikolay V. Melnik, Vladimir I. Eremets, Larisa A. Neminuschaya, Valentina I. Klyukina, Svetlana A. Gryn, Evgenia V. Markova, Irina N. Matveeva, & Sergey Yu. Smolentsev. (2020). Efficiency of probiotics use in treatment of calves. International Journal of Research in Pharmaceutical Sciences, 11(2), 1674–1678. Retrieved from https://ijrps.com/home/article/view/926

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