Prescription Pattern of Antimicrobial Agents in Various Dental Clinics at Malabar Region of Kerala, South India
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Antimicrobial Agents, Prescription Pattern, Amoxicillin, Drug Utilization, Dental Practice
Abstract
Antimicrobial agents (AMAs) are among the most commonly prescribed drugs in dental practice. However inappropriate prescribing and irrational use of antimicrobial agents without prior culture and sensitivity tests, inadequate duration, dosing etc. have been identified as major factors contributing to the emergence of antibiotic resistance, which is an ongoing challenge in all over the world. A total of 1900 patients were screened and out of which 1748 patients were selected based on the inclusion and exclusion criteria for the study after taking consent. This study shows that the majority of patients attended in these clinics were female, 1020 (58.35%) and majority of patients (717) comes under age group 21-40 (41.02%) followed by age group by ≤ 20 (32.43%). This study established that most commonly recommended antimicrobial agents were amoxicillin, followed by amoxicillin-clavulanate and metronidazole. The antimicrobial agents like Ciprofloxacin, Cefixime, Tetracyclines, Azithromycines were also used but in less extent. This study also revealed that the selection of antimicrobials was not confirmed with culture and sensitivity tests in all cases, which may negatively influence bacterial resistance profile.
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References
AbdulKader, H. K., Ali, S. M., Hassan, M. I. A., Manan, M. M. 2010. Knowledge of Prescribing Antimicrobial Among Dental Practitioners in Klang Valley Region. Malaysian Dental Journal, 31(1):35–43.
Abraham, S. B., Abdulla, N., Himratul-Aznita, W. H., Awad, M., Samaranayake, L. P., Ahmed, H. M. A. 2020. Antibiotic prescribing practices of dentists for endodontic infections; a cross-sectional study. PLOS ONE, 15(12):e0244585.
Al-Haroni, M., Skaug, N. 2006. Knowledge of prescribing antimicrobials among Yemeni general dentists. Acta Odontologica Scandinavica, 64(5):274–280.
Al-Haroni, M., Skaug, N. 2007. Incidence of antibiotic prescribing in dental practice in Norway and its contribution to national consumption. Journal of Antimicrobial Chemotherapy, 59(6):1161–1166.
Andersson, L., Andreasen, J. O., Day, P., Heithersay, G., Trope, M., DiAngelis, A. J., Kenny, D. J., Sigurdsson, A., Bourguignon, C., Flores, M. T., Hicks, M. L., Lenzi, A. R., Malmgren, B., Moule, A. J., Tsukiboshi, M. 2016. Guidelines for the Management of Traumatic Dental Injuries: 2. Avulsion of Permanent Teeth. Pediatric Dentistry, 38(6):369–376.
Dar-Odeh, N., Fadel, H. T., Abu-Hammad, S., Abdeljawad, R., Abu-Hammad, O. A. 2018. Antibiotic Prescribing for Oro-Facial Infections in the Paediatric Outpatient: A Review. 7(2):38.
Fayisa, K., Anas, P. P., Sudhakar, A. 2019. Drug utilization patterns of antibiotics in outpatient department of educare dental hospital at Malappuram, Kerala, India. International Journal of Basic and Clinical Pharmacology, 8:930–933.
Fleming-Dutra, K. E., Hersh, A. L., Shapiro, D. J., Enns, E. A., File, T. M., Finkelstein, J. A., Gerber, J. S., Hyun, D. Y., Linder, J. A., Lynfield, R., Margolis, D. J., May, L. S., Merenstein, D., Metlay, J. P., Newland, J. G., Piccirillo, J. F., Roberts, R. M., Sanchez, G. V., Suda, J., Thomas, A., Woo, T. M., Zetts, R. M., Hicks, A. 2016. Prevalence of Inappropriate Antibiotic Prescriptions Among US Ambulatory Care Visits, 2010-2011. JAMA, 315(17):1864–1873.
Haliti, F., Krasniqi, S., Gllareva, B., Shabani, N., Krasniqi, L., Haliti, N. 2017. Antibiotic Prescription Patterns in Ambulatory Dental Care in Kosovo Abstract. Oral Health and Dental Management, 16(1):1–5.
Jayanthi, M. K., Sushma, N. V. 2014. Drug utilization pattern and pharmacoeconomic study in paediatric dentistry at a tertiary hospital. International Journal of Pharmacy and Pharmaceutical Sciences, 6(2):70–72.
Kaul, R., Angrish, P., Jain, P., Saha, S., Sengupta, A. V., Mukherjee, S. 2018. A Survey on the Use of Antibiotics among the Dentists of Kolkata, West Bengal, India. International Journal of Clinical Pediatric Dentistry, 11(2):122–127.
Krishnakumar, J., Tsopra, R. 2019. What rationale do GPs use to choose a particular antibiotic for a specific clinical situation? BMC Family Practice, 20(1):178.
Muhas, C., Salim, C. M., Mufeeda, T. P., Shamna, M. 2018. Prescription pattern of anti-diabetic drugs in a rural area of South Malabar region of Kerala, South India. International Journal of Research in Medical Sciences, 6(12):4082–4086.
Padda, S., Goyal, G., Kaur, B. 2016. Prescription pattern of drugs among general dentists in north India. International Journal of Current Research, 8(5):32243–32247.
Roda, R. P., Bagan, J. V., Bielsa, J. M. S., Pastor, E. C. 2007. Antibiotic use in dental practice. A review. Medicina Oral, Patologia Oral y Cirugia Bucal, 12(3):E186–E192.
Standing Medical Advisory Committee 1998. Sub-Group on Antimicrobial Resistance. The Path of Least Resistance. London: Stationery Office, Accessed on: 25 Oct 2021.
Suhaib, M., Ahmad, F., Ahmad, M. 2017. Prescription Pattern of Antimicrobial Agents Among Dental Practitioners in a Tertiary Care Centre in North India. Asian Journal of Pharmaceutical and Clinical Research, 10(4):192.
Weber, J. T., Courvalin, P. 2005. An Emptying Quiver: Antimicrobial Drugs and Resistance. Emerging Infectious Diseases, 11(6):791–793.
Whitten, B. H., Gardiner, D. L., Jeansonne, B. G., Lemon, R. R. 1996. Current Trends in Endodontic Treatment: Report of a National Survey. The Journal of the American Dental Association, 127(9):1333–1341.
Yingling, N. M., Byrne, B. E., Hartwell, G. R. 2002. Antibiotic Use by Members of the American Association of Endodontists in the Year 2000: Report of a National Survey. Journal of Endodontics, 28(5):396–404.
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