Phytochemical and Hepatoprotective Activity of Prosopis juliflora Barks on Different Models

Hemamalini  K; Sadanandam  Palle; Kanakam  Vijayabhaskar; Supraja

doi:10.26452/ijrps.v14i3.4308

Hemamalini K ⁽¹⁾ , Sadanandam Palle ⁽²⁾ , Kanakam Vijayabhaskar ⁽³⁾ , Supraja ⁽⁴⁾

(1) Swami Vivekananda Institute of pharmaceutical sciences, Vangapally, Yadagirigutta, India ,

(2) Chemistry Department, Malla reddy Engineering College, Hyderabad, India ,

(3) Department of Pharmacognosy, Bomma Institute of Pharmacy, Alipuram, Telangana, India, India ,

(4) Swami Vivekananda Institute of pharmaceutical sciences, Vangapally, Yadagirigutta, India

https://doi.org/10.26452/ijrps.v14i3.4308

Issue
Vol. 14 No. 3 (2023): Volume 14 Issue 3

Keywords:

Methanolic Extract, Barks, Prosopis juliflora, Hepatoprotective activity

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Abstract

Liver injury is a common disorder where natural remedies are practiced from ancient time from plant source which shows alternative treatment in a safe manner. The Hepatoprotective activity of methanolic extract of Prosopis juiliflora bark part was taken for evaluation in screening. The model chosen for the study is carbon tetrachloride (0.1ml/kg) and the standard drug silymarin of 20mg/kg was used for the study for 21 days. The hepatoprotective effect of the methanolic extract against the carbon tetrachloride-induced hepatotoxicity in wistar rats has been demonstrated by the substantial and severe reduction of enzymes in the serum.

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Authors

Hemamalini K

Swami Vivekananda Institute of pharmaceutical sciences, Vangapally, Yadagirigutta

rkhemamalini@gmail.com (Primary Contact)

Sadanandam Palle

Chemistry Department, Malla reddy Engineering College, Hyderabad

Kanakam Vijayabhaskar

Department of Pharmacognosy, Bomma Institute of Pharmacy, Alipuram, Telangana, India

Supraja

Swami Vivekananda Institute of pharmaceutical sciences, Vangapally, Yadagirigutta

K, H. ., Palle, S. ., Vijayabhaskar, K. ., & Supraja. (2023). Phytochemical and Hepatoprotective Activity of Prosopis juliflora Barks on Different Models. International Journal of Research in Pharmaceutical Sciences, 14(3), 153–160. https://doi.org/10.26452/ijrps.v14i3.4308