Effect of natural antioxidants and important herbal medicines on blood infections and sepsis: A systematic review

Abstract

Phytochemical and pharmaceutical studies have shown that medicinal plants are rich sources of antioxidant and biologically active compounds. The medicinal plants can have inhibitory effects on various types of parasitic diseases, microbial infections, blood infections, and sepsis. This review was done to report important medicinal plants effective on the prevention and treatment of blood infections and sepsis. Based on the results obtained from the review of numerous articles, indexed in the databases Information Sciences Institute, Scopus, PubMed, and Google Scholar etc., the most important medicinal plants effective in the treatment and prevention of sepsis and parasitic, microbial, and viral blood infections are Veronica officinalis, Allium sativum, Paeonia lactiflora, Angelica Sinensis, Hippophae rhamnoides, Melissa officinalis, Ziziphus Spina-Christi, Astragalus species, Salvia miltiorrhiza, Rheum palmatum, Sophora flavescens, Scutellaria species, Phyllanthus amarus, Calendula officinalis, Scrophularia striata, Lawsonia inermis, Artemisia species, and Plantago major. Sterolic, luteolin, tannins, quercetin, saponins and some other bioactive ingredients are the most important bioactive compounds and flavonoids of these medicinal plants that may be used in producing new anti-blood infections and anti-sepsis drugs.