Antidandruff activity of Eclipta alba (l.) Hassk. and Lippia nodiflora linn

Regupathi T. (1) , Chitra K. (2)
(1) Ultra College of Pharmacy, Madurai – 625 104, Tamil Nadu, India, India ,
(2) Sri Ramachandra University, Chennai – 600 116, Tamil Nadu, India, India

Abstract

This experiment was subjected to investigate anti dandruff properties of ethanolic extract and isolated compound of Eclipta alba and Lippia nodiflora. The plant specimen for the proposed study E. alba and L. nodiflora was collected from the wetland fields and other irrigated fields in and around Madurai and ethanolic extracts were prepared. Invitro anti dandruff activity was performed using the disc diffusion assay. Suspension containing 5 x 10 6 CFU / ml of dandruff causing organism, Malassezia furfur was swabbed on the surface of the sterile SDA plates using a sterile cotton swab. Sterile filter paper discs impregnated with the isolated compound doses viz., 25 µg / ml and 50 µg / ml and ethanolic extract's dose level of 250 µg / ml and 500 µg / ml per disc was aseptically placed over the seeded SDA plates. Similarly antibiotic disc of clotrimazole was used as standard drug for comparison of antifungal activity. With this interest, we investigated the anti dandruff activities of E. alba and L. nodiflora against Malassezia furfur by exposure to extract and also isolated compound by disc diffusion method. From our study, it was found that the M. furfur was more sensitive to all the concentrations of ethanolic extract and isolated compound of the two tested medicinal plants.

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Authors

Regupathi T.
poornareg@yahoo.co.in (Primary Contact)
Chitra K.
Regupathi T., & Chitra K. (2015). Antidandruff activity of Eclipta alba (l.) Hassk. and Lippia nodiflora linn. International Journal of Research in Pharmaceutical Sciences, 6(2), 185–188. Retrieved from https://ijrps.com/home/article/view/3969

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