Evaluation of antibacterial and antitubercular activities of Cassia fistula Linn root

Channabasappa Hallikeri S. (1) , Shrinivas Joshi D. (2) , Venkatrao Kulkarni H. (3)
(1) Centre for Research and Development, Prist University, Thanjavur, Tamil Nadu 613403, India / Novel Drug Design and Discovery Laboratory, Department of Pharmaceutical Chemistry, S.E.T’s College of Pharmacy, Sangolli Rayanna Nagar, Dharwad-580002, Karnataka, India, India ,
(2) Novel Drug Design and Discovery Laboratory, Department of Pharmaceutical Chemistry, S.E.T’s College of Pharmacy, Sangolli Rayanna Nagar, Dharwad-580002, Karnataka, India, India ,
(3) Novel Drug Design and Discovery Laboratory, Department of Pharmaceutical Chemistry, S.E.T’s College of Pharmacy, Sangolli Rayanna Nagar, Dharwad-580002, Karnataka, India, India

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Vol. 6 No. 1 (2015): Volume 6 Issue 1
Keywords:
    Alcohol extract, Antibacterial, Antitubercular, Cassia fistula, Root
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Abstract

The different extracts of Cassia fistula Linn root were evaluated for antibacterial and antitubercular activities against different Gram-positive, Gram-negative bacterial strains and M. tuberculosis H37Rv strain using ciprofloxacin, norfloxacin and isoniazid as standard drugs, respectively. Alcoholic extract showed significant activity against Bacillus subtilis, while this extract was found to show moderate activity against Escherichia coli. Alcoholic extract also showed good antitubercular activity. The presence of alkaloids and tannins in alcoholic extract could be attributed for the antibacterial and antitubercular activities.

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Authors

Channabasappa Hallikeri S.
Centre for Research and Development, Prist University, Thanjavur, Tamil Nadu 613403, India / Novel Drug Design and Discovery Laboratory, Department of Pharmaceutical Chemistry, S.E.T’s College of Pharmacy, Sangolli Rayanna Nagar, Dharwad-580002, Karnataka, India
Shrinivas Joshi D.
Novel Drug Design and Discovery Laboratory, Department of Pharmaceutical Chemistry, S.E.T’s College of Pharmacy, Sangolli Rayanna Nagar, Dharwad-580002, Karnataka, India
shrinivasdj@rediffmail.com (Primary Contact)
Venkatrao Kulkarni H.
Novel Drug Design and Discovery Laboratory, Department of Pharmaceutical Chemistry, S.E.T’s College of Pharmacy, Sangolli Rayanna Nagar, Dharwad-580002, Karnataka, India
Channabasappa Hallikeri S., Shrinivas Joshi D., & Venkatrao Kulkarni H. (2015). Evaluation of antibacterial and antitubercular activities of Cassia fistula Linn root. International Journal of Research in Pharmaceutical Sciences, 6(1), 82–84. Retrieved from https://ijrps.com/home/article/view/3908
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