Biochemical study of the association between serum level of Zinc, Copper and Selenium with hormone of thyroid in thyroid disorders

Abstract

The current study has been performed in AL-Hussein General Hospital, Imam Zine ALabiden Hospital, and one clinic in Karbala to determine the value of thyroid hormone including T3 triiodothyronine, T4 tetraiodothyronine, thyroid stimulating hormone and the concentration of Zinc, Copper and Selenium in patients with thyroid disorders of hyperthyroidism 31 and hypothyroidism 26 and their relation. All patients are females in the age of 20 to 55 years old beside the control groups including 50 healthy females selected from the medical staffs or patients' relatives carrying out no signs and symptoms of thyroid disorders. The results of the study have shown that the concentration of serum zinc and copper in females with hyperthyroidism is higher than the control group (p <0.001), also the concentration of serum selenium in patient with hyperthyroidism is lower than control group (p<0.001), subsequently, the concentration of serum zinc, copper and selenium in females with hyperthyroidism is lower than control group (p <0.001) and the concentration of serum zinc in females with hyperthyroidism is lower than control group (p <0.001).