Gene expression and histological evaluation of the effect of local exogenous application of Morin /Moringa oleifera on wound healing in rats

Abstract

This study aimed to study the effect of local application of Moran and Moringa Oliveira on wound healing in rats, 60 rats of white male rats, and surgical skin (width 2 cm and depth 0.5-0.6 cm) on the skin. From the cheek of the animal and divided into four groups, the control group, Morin group, Moringa group oleifera and Morin (Moringa oleifera) group, animal scratching was performed for healing periods (2,4 and 7 days), histological cells were found inflammatory, Skin, and contracted wound healing in all animal samples for all healing periods. The gene profile was analyzed in biopsies of previously injured skin and treated murine compared with the molecular-treated molybdenum skin by Mygene Bioneer Korea. Upregulation of IL-6, IL-1β1, CYP1B1 and CXCL1 gene expression and downregulation of psoriasin mRNA identified in samples treated topically with Morin.