Floating drug delivery systems: A review

Arunachalam A. (1) , Karthikeyan M. (2) , Kishore Konam (3) , Pottabathula Hari Prasad (4) , Sethuraman S. (5) , Ashutoshkumar S. (6) , Manidipa S. (7)
(1) Department of Pharmaceutics, Sasikanthreddy College of Pharmacy, Nellore, Andhra Pradesh, India, India ,
(2) Department of Pharmaceutics, AKRG College of Pharmacy, West Godavari, Andhra Pradesh, India, India ,
(3) Department of Pharmaceutical Analysis and QA, Sree Nagarjuna College of Pharmacy, Kadipikonda, Warangal, Andhra Pradesh, India, India ,
(4) Department of Industrial Pharmacy, Swami Ramananda Tritha Institute of Pharmaceutical Sciences, Nalkonda, Andhra Pradesh, India, India ,
(5) Department of Chemistry, SCSVMV University, Kanchipuram, Tamilnadu, India, India ,
(6) Department of Pharmaceutics, AKRG College of Pharmacy, West Godavari, Andhra Pradesh, India, India ,
(7) Department of Pharmaceutics, AKRG College of Pharmacy, West Godavari, Andhra Pradesh, India, India

Abstract

The purpose of writing this review on floating drug delivery systems (FDDS) was to compile the recent literature with special focus on the principal mechanism of floatation to achieve gastric retention. The recent developments of FDDS including the physiological and formulation variables affecting gastric retention, approaches to design single-unit and multiple-unit floating systems, and their classification and formulation aspects are covered in detail. This review also summarizes the in vitro techniques, in vivo studies to evaluate the performance and application of floating systems, and applications of these systems. These systems are useful to several problems encountered during the development of a pharmaceutical dosage form.

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Authors

Arunachalam A.
harisarun1985@gmail.com (Primary Contact)
Karthikeyan M.
Kishore Konam
Pottabathula Hari Prasad
Sethuraman S.
Ashutoshkumar S.
Manidipa S.
Arunachalam A., Karthikeyan M., Kishore Konam, Pottabathula Hari Prasad, Sethuraman S., Ashutoshkumar S., & Manidipa S. (2011). Floating drug delivery systems: A review. International Journal of Research in Pharmaceutical Sciences, 2(1), 76–83. Retrieved from https://ijrps.com/home/article/view/3059

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