Antimicrobial activity of extractives of Solidago canadensis L.

Abstract

The anti - bacterial activity of various extracts viz., Hexane, Chloroform, Ethyl acetate and 50% Aqueous – ethanol of the whole plant of Solidogo candensis L was studied by disc diffusion method using Muller Hinton Agar media and the zone of inhibition for various extracts was compared with that of standard Ciprofloxacin (5 micrograms / disc). All extract showed potential anti – bacterial activity comparable to that of the standard drug against the tested organisms. The MIC for various extracts was 300 micrograms / ml for Hexane and Chloroform extract and 200 micrograms / ml for ethyl acetate and 50% aqueous – ethanol extract. Where, hexane showed MIC of 200 micrograms / ml except for Salmonella typhi which was as comparable with that of the standard Ciprofloxacin (5 micrograms / disc). Hence the present study brought to light the scientific data documentation with respect to the anti – infective property of the plant Solidogo candensis L.