Chemoprevention of oral cancer using tretinoin biofilm - A review

Harini M (1) , Gheena S (2) , Gayathri R (3)
(1) Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai – 600077, Tamil Nadu, India, India ,
(2) Department of Oral Pathology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai – 600077, Tamil Nadu, India, India ,
(3) Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai – 600077, Tamil Nadu, India, India

Abstract

Oral cancer is a major disease prevalent all over the world. Oral squamous cell carcinoma (OSCC) is a well-known disorder that accounts for more than 90% of all oral cancers. Five percent of all tumors occur in the head and neck, and approximately half of those occur specifically pertaining to the oral cavity. Tretinoin biofilm is a cost-effective alternative method used in the chemoprevention of oral cancer. All relevant search engines (google scholar, PubMed, etc.) searched for the literature pertaining to oral cancer, chemopreventive methods and the use of Tretinoin 'biofilm' in oral cancer prevention. The data was collected, and quality analysis of the collected data was done. The knowledge in the current point of time analysed and thus the consensus was established. Oral cancer has proved to be a major disease with major health issues leading to morbidity and mortality among the patients. The treatment for oral cancer is expensive and invasive and hence cannot be approached by everyone, leading to unfortunate consequences. This technique if successful, has the potential to be employed worldwide to treat oral cancer patients leading to the betterment of health and lifestyle.

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Authors

Harini M
Gheena S
gheena@saveetha.com (Primary Contact)
Gayathri R
Harini M, Gheena S, & Gayathri R. (2020). Chemoprevention of oral cancer using tretinoin biofilm - A review. International Journal of Research in Pharmaceutical Sciences, 11((SPL 3), 1121–1125. Retrieved from https://ijrps.com/home/article/view/2925

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