In vitro anthelmintic activity of Fenugreek seeds extract against Pheritima posthuma

Chandrashekhar D. Khadse (1) , Rajendra B. Kakde (2)
(1) MES, College of Pharmacy, Sonai, Tal. Newasa, Dist. Ahmednagar-414105 Maharashtra, India, India ,
(2) Department of Pharmaceutical Science, RTM, Nagpur University, Nagpur, Maharashtra, India, India

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Vol. 1 No. 3 (2010): Volume 1 Issue 3
Keywords:
    Anthelmintic activity, Trigonella foenum-graecum, Pheritima posthuma, Fenugreek
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Abstract

Crude extracts of Trigonella foenum-graecum (Leguminoceae) were evaluated for in-vitro anthelmintic activity on the Indian adult earthworms Pheritima posthuma. The seed extracts of Trigonella foenum-graecum had shown a dose dependant inhibition of spontaneous motility (Paralysis) of earthworms. It has been observed that alcoholic extract (60mg/ml) has shown anthelmintic activity, which was compared with albendazole as reference drug. Therefore the seeds could be categorized under anthelmintic herbal drugs and could become a potent key ingredient of such herbal formulation.

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Authors

Chandrashekhar D. Khadse
MES, College of Pharmacy, Sonai, Tal. Newasa, Dist. Ahmednagar-414105 Maharashtra, India
khadsecd@gmail.com (Primary Contact)
Rajendra B. Kakde
Department of Pharmaceutical Science, RTM, Nagpur University, Nagpur, Maharashtra, India
Chandrashekhar D. Khadse, & Rajendra B. Kakde. (2010). In vitro anthelmintic activity of Fenugreek seeds extract against Pheritima posthuma. International Journal of Research in Pharmaceutical Sciences, 1(3), 267–269. Retrieved from https://ijrps.com/home/article/view/2916
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