Gender difference in cruciate ligament of the knee in normal condition and the risk to its injury; an updated review

Yasser Alharbi (1)
(1) Department of Basic Medical Sciences, College of Medicine, King Saud Bin Abdul Aziz University for Health Sciences, (KSAU-HS, King Abdullah International Medical Research Center (KAIMRC), National Guard Health Affair (NGHA), King Abdulaziz Medical City, Jeddah, Saudi Arabia, Saudi Arabia

Abstract

Anterior cruciate ligament is a broad intracapsular stabilising ligament in the knee joint. Anterior cruciate ligament tears are one of the commonest injuries occurring to athletes. Numerous studies have investigated the epidemiology and risk factors to anterior Cruciate Ligament injury. It has been documented that anterior Cruciate Ligament tears are more common among females. In this review, we presented a collective summary of cruciate ligaments variations between genders in normal conditions and in different illnesses. Moreover, we illustrated the different response between genders to trauma and stressors as regards the effect on the cruciate ligaments. We also presented a summary of the risk factors and types of injury to the cruciate ligaments in response to different modes of trauma. We summarized the most prevalent, recent and evidence-based risk factors of anterior Cruciate Ligament injuries which include genetic, hormonal, anatomical, environmental, biomechanical and neuromuscular risk factors. We emphasized on the relationship between age, hormones and the incidence of anterior cruciate ligament injuries during puberty, older ages and changes accompanying menstrual cycles. We conclude that risk factors are numerous, but the higher prevalence in females can be predictable based on these factors and therefore preventable. However, further studies are required to deeper investigate the recovery predictive factors after injury and determine better approaches to tackle these risk factors.

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Authors

Yasser Alharbi
Algaidyy@gmail.com (Primary Contact)
Yasser Alharbi. (2021). Gender difference in cruciate ligament of the knee in normal condition and the risk to its injury; an updated review. International Journal of Research in Pharmaceutical Sciences, 12(3), 2215–2225. Retrieved from https://ijrps.com/home/article/view/262

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