Histomorphological Study of Lower Gastrointestinal Tract Lesions in Per Rectal Bleeding Cases

Abstract

The present study on the histomorphology of lower gastrointestinal tract lesions in patients presenting with per rectal bleeding was two years (June 2015 to May 2017) cross-sectional study carried out in the department of pathology of a tertiary care hospital and included 40 cases. Constipation was the most typical associated symptom along with per rectal bleeding. Clinical details and radiological investigations helped in making the diagnosis of all lesions of the lower gastrointestinal tract causing per rectal bleeding. The mean age at presentation in benign lesions was 33 years, while the mean age at presentation in malignant lesions was 61 years. The mean age at presentation of adenocarcinoma was 62 years. Majority of cases of adenocarcinoma presented with Astler-Coller stage C1. The other malignancies of the lower gastrointestinal tract causing per rectal bleeding were clonogenic carcinoma, neuroendocrine carcinoma and moderately differentiated squamous cell carcinoma. The most common cause of per rectal bleeding amongst the lower gastrointestinal tract is a neoplastic lesion. The lesions of the lower gastrointestinal tract causing per rectal bleeding are seen more commonly in male patients with a predominant age group of above 40 years, and constipation is the most typical associated symptom in these cases. The most common cause of per rectal bleeding amongst the lower gastrointestinal tract is a neoplastic lesion.