Assessment of serum biochemical profile in breast cancer patients

Srinivas V (1) , Balasankar R (2) , Prathyusha K (3) , Manisha Patel K (4) , Sharvana Bhava B S (5) , Venkateshwarlu E (6)
(1) Department of Oncology, KMC/MGM Hospital, KNR University, Warangal-506 007, Telangana, India, India ,
(2) Department of Oncology, KMC/MGM Hospital, KNR University, Warangal-506 007, Telangana, India, India ,
(3) Department of Clinical Pharmacy, Vaagdevi College of Pharmacy, Kakatiya University, Warangal-506 007, Telangana, India, India ,
(4) Department of Clinical Pharmacy, Vaagdevi College of Pharmacy, Kakatiya University, Warangal-506 007, Telangana, India, India ,
(5) Department of Clinical Pharmacy, Vaagdevi College of Pharmacy, Kakatiya University, Warangal-506 007, Telangana, India, India ,
(6) Department of Clinical Pharmacy, Vaagdevi College of Pharmacy, Kakatiya University, Warangal-506 007, Telangana, India, India

Abstract

Cancer occurrence and it's connected mortality on the rise and has become a significant general wellbeing concern. As of now, it is the subsequent driving reason for death around the globe. Bosom malignant growth is the world's most basic malignant growth in ladies with high mortality rate. This study was planned to evaluate the ailment movement and metastasis. The current investigation is a close, observational examination. One hundred seven female bosom disease patients over the age of 35 years were enlisted to examine varieties in serum biochemical profile of bosom malignant growth patients. In this investigation, the mean estimations of Blood urea nitrogen, Uric corrosive, White platelets and Neutrophil lymphocyte proportion were discovered to be diminished, and that of Serum creatinine, Serum glutamic oxaloacetic transaminase, serum glutamic pyruvic transaminase, Alkaline phosphatase, Fasting glucose, neutrophils and lymphocytes were discovered to be expanded from first to fourth patterns of chemotherapy. The obtained parameters were expressed as Mean ± SD, and the parameters were compared by using paired t-test. All Biochemical parameters should be monitored after every chemotherapy cycle until the completion of a planned treatment regimen. The changes in biochemical parameters provide an opportunity to explain the degree of risk in breast cancer patients by metastasis which helps to avoid further worsening of the disease.

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Authors

Srinivas V
Balasankar R
sankarrmc2004@gmail.com (Primary Contact)
Prathyusha K
Manisha Patel K
Sharvana Bhava B S
Venkateshwarlu E
Srinivas V, Balasankar R, Prathyusha K, Manisha Patel K, Sharvana Bhava B S, & Venkateshwarlu E. (2020). Assessment of serum biochemical profile in breast cancer patients. International Journal of Research in Pharmaceutical Sciences, 11(4), 7775–7781. Retrieved from https://ijrps.com/home/article/view/2451

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