A Concise Review on Targeted Therapy for Oral Cancer

Thariny E (1) , Ezhilarasan D (2) , Brundha M.P (3)
(1) Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai-77, Tamilnadu, India, India ,
(2) Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai-77, Tamil Nadu, India, India ,
(3) Department of General Pathology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai-77, Tamilnadu, India, India

Abstract

Oral Cancer has become a center of attraction in the world, causing health problems. Carcinoma that involves the lip, tongue, mouth surface, palate, and throat is also serious if not diagnosed and treated. Current treatment strategies involve surgical removal, using chemotherapeutic drugs and radiation therapy. The event of targeted  therapy aid in medicine together with oral cancers is that the basic dependence of neoplasm cells on biological pathways which might be coupled to medicine that inhibit those pathways. The resistance of tumor cells to anticancer drugs is a known method which is investigated experimentally at the molecular level. Immunotherapeutic agent resistance is thought to affect the efficacy of anticancer remedies. The induced or intrinsic drug resistance has a strong effect on the survival and cancer growth prognosis by suppression of cancer-associated cell signaling pathways of cancer patients. Targeted therapy also has a significant inhibitory ability, thus demonstrating the high quality of treatment. Hence this concise review discusses the implementation of molecular targeted therapy in the treatment of oral cancer.

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Authors

Thariny E
Ezhilarasan D
ezhilarasand.sdc@saveetha.com (Primary Contact)
Brundha M.P
Thariny E, Ezhilarasan D, & Brundha M.P. (2020). A Concise Review on Targeted Therapy for Oral Cancer. International Journal of Research in Pharmaceutical Sciences, 11((SPL 3), 84–90. Retrieved from https://ijrps.com/home/article/view/2371

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