Evaluation of In-Vitro Antioxidant Activity of Root Bark Extracts of Ventilago Maderspatana Gaertn

Manish Deshmukh (1) , Ashish Budhrani (2) , Upendra Gandagule (3) , Sanjay Nagdev (4) , Mayur Bhurat (5) , Sourabh Kosey (6) , Mrinal Sharma (7) , Rupal Bhurat (8)
(1) Datta Meghe College of Pharmacy, Datta Meghe Institute of Medical Sciences (DU), Wardha, Pin-442001, Maharashtra, India, India ,
(2) Datta Meghe College of Pharmacy, Datta Meghe Institute of Medical Sciences (DU), Wardha, Pin-442001, Maharashtra, India, India ,
(3) KYDSCT’s College of Pharmacy, Sakegaon, Pin-425201, Maharashtra, India, India ,
(4) Shri. Prakash Chand Jain College of Pharmacy & Research Palaskheda (Bk), Jamner, Pin-424206, Maharashtra, India, India ,
(5) Shri. Prakash Chand Jain College of Pharmacy & Research Palaskheda (Bk), Jamner, Pin-424206, Maharashtra, India, India ,
(6) ISF College of Pharmacy, Moga, Pin-142001, Punjab, India, India ,
(7) Dreamz College of Pharmacy, Sundernagar, Pin-175019, Himachal Pradesh, India, India ,
(8) Shri. Prakash Chand Jain College of Pharmacy & Research Palaskheda (Bk), Jamner, Pin-424206, Maharashtra, India, India

Abstract

Ventilago maderspatana Gaertn. is a plant having enormous biomedical potential. It is a plant in the Indian system of medicine having a plethora of properties and applications and The root barks powder of Ventilago maderspatana Gaertn. have many properties and applications like it are used as a stomachic, tonic, carminative, stimulant. It is also useful in the treatment of weakness and fever. For further investigations of activities like anti-oxidant activity, In-vitro anti-oxidant studies were done on root bark extracts of Ventilago maderspatana Gaertn. (Family Rhamnaceae) by using standard methods like Lipid peroxidation Assay, Estimation of total anti-oxidant capacity (TAC), Hydroxyl radical scavenging activity, Nitric oxide inhibition radical activity by p-Nitroso dimethyl aniline method, and ABTS Radical scavenging method. The root barks of plant Ventilago maderspatana Gaertn. Were subjected to cold maceration process in 3-liter Round bottom flask using ethanol and distilled water and nature and yield was noted and stored at 40C in the refrigerator until further use and both the extracts were labelled as Ventilago maderspatana Gaertn. Root Bark aqueous (VMRBA) and Ventilago maderspatana Gaertn. Root Bark Ethanolic (VMRBE) for convenient identification. Ethanolic extract of Root Bark showed the more potent anti-oxidant activity than aqueous Root Bark extract of Ventilago maderspatana Gaertn.

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Authors

Manish Deshmukh
Ashish Budhrani
ashu.budhrani123@gmail.com (Primary Contact)
Upendra Gandagule
Sanjay Nagdev
Mayur Bhurat
Sourabh Kosey
Mrinal Sharma
Rupal Bhurat
Manish Deshmukh, Ashish Budhrani, Upendra Gandagule, Sanjay Nagdev, Mayur Bhurat, Sourabh Kosey, Mrinal Sharma, & Rupal Bhurat. (2020). Evaluation of In-Vitro Antioxidant Activity of Root Bark Extracts of Ventilago Maderspatana Gaertn. International Journal of Research in Pharmaceutical Sciences, 11((SPL 4), 1636–1640. Retrieved from https://ijrps.com/home/article/view/2252

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