Evaluation of Risk Factors in Abnormal Uterine Bleeding and its Management in Tertiary Care Hospital

Anusha K; Manisha B; Cherukuri Anusha; Hina Sultana; Neelam Injeti

Anusha K ⁽¹⁾ , Manisha B ⁽²⁾ , Cherukuri Anusha ⁽³⁾ , Hina Sultana ⁽⁴⁾ , Neelam Injeti ⁽⁵⁾

(1) Department of Pharm D, CMR College of Pharmacy, Kandlakoya, Medchal-501401, Telangana, India, India ,

(2) Department of Pharm D, CMR College of Pharmacy, Kandlakoya, Medchal-501401, Telangana, India, India ,

(3) Department of Pharm D, CMR College of Pharmacy, Kandlakoya, Medchal-501401, Telangana, India, India ,

(4) Department of Pharm D, CMR College of Pharmacy, Kandlakoya, Medchal-501401, Telangana, India, India ,

(5) Department of Pharm D, CMR College of Pharmacy, Kandlakoya, Medchal-501401, Telangana, India, India

Issue
Vol. 12 No. 2 (2021): Volume 12 Issue 2

Keywords:

Abnormal Uterine Bleeding, Risk Factors, Diagnostic Tools, Uterine Bleeding Management, Anticoagulants

PDF LaTeX HTML epub

Abstract

To evaluate risk factors in abnormal uterine bleeding and its management in tertiary care hospital. It is a prospective observational study carried out for a period of 6 months in the in-patient and out-patients department of Gynaecology. A total of 306 cases were analyzed out of that 88 cases had meaningful data for analysis. Most common risk factor observed in our study was Leiomyoma(29%). Major percentage of risk was observed in the age group 31-45years (64%). The diagnostic method used for screening and confirmation of AUB was USG Abdomen in 63 patients (58%). Most of the Out-patients and few in-patients were administered with anti-fibrinolytics to control heavy bleeding and along with combinational hormonal therapy for hormonal imbalance patients. The surgical procedure carried out was hysterectomy (53%).In the present study, drug induced uterine bleeding were not observed. In our study, abnormal uterine bleeding occurring without any known risk factors that can be included into the category of NOT YET CLASSIFIED according to PALM-COEIN classification, as to which physicians must be more cautious towards the patients visiting at Out- patient departments as it may lead to serious complications.

Full text article

Generated from XML file

References

Anupamasuresh, Y., Suresh, Y., Jain, P. 2014. Abnormal uterine bleeding: a clinic histopathological analysis. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, pages 656–661.

Byna, P., Siddula, S., Kolli, S., Shaik, M. 2015a. Histopathological correlation of abnormal uterine bleeding in perimenopausal women. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 4(6):1875–1878.

Byna, P., Siddula, S., Kolli, S., Shaik, M. 2015b. Thyroid abnormality in perimenopausal women with abnormal uterine bleeding. International Journal of Research in Medical Sciences, pages 3250–3253.

Davis, E., Sparzak, B. 2019. Abnormal Uterine Bleeding (Dysfunctional Uterine Bleeding). ln: Stat Pearls [Internet]. Treasure Island (FL): Stat Pearls Publishing, Accessed on: 20 March 2019.

Giannella, L., Cerami, L. B., Setti, T., Bergamini, E., Boselli, F. 2019. Prediction of Endometrial Hyperplasia and Cancer among Premenopausal Women with Abnormal Uterine Bleeding. BioMed Research International, page 8598152.

Godin, R., Marcoux, V., Tagalakis, V. 2017. Abnormal uterine bleeding in women receiving direct oral anticoagulants for the treatment of venous thromboembolism. Vascular Pharmacology, 93-95(1- 5):1–5.

Gowri, M., Radhika, B., Harshini, V., Ramaiaha, R. 2014. Role of thyroid function tests in women with abnormal uterine bleeding. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, pages 54–57.

Guin, G., Sandhu, S. K., Lele, A., Khare, S. 2011. Hysteroscopy in Evaluation of Abnormal Uterine Bleeding. The Journal of Obstetrics and Gynecology of India, 61:546–549. ISSN: 0971-9202, 0975- 6434.

Hiralal, K. 2014. Dc Dutta’S Textbook of Gynecology. 6th edition Nov’13 Jayshree brother medical publisher (P) Ltd. Pg-185-197, ISBN: 978-93- 5152-068-9.

Hooja, N., Singh, N. Premlata Mital, P., Bhargava, S., Kumawat, A. 2016. Relationship of education and socio-economic status with knowledge about abnormal uterine bleeding and its risk factors. International Journal of Community Medicine and Public Health, pages 2229–2232.

Kanthi, J. M., Remadevi, C., Sumathy, S., Sharma, D., Sreedhar, S., Jose, A. 2016. Clinical study of endometrial polyp and role of diagnostic hysteroscopy and blind avulsion of polyp. Journal of clinical and diagnostic research, 10(6).

Kinay, T., Basarir, Z. O., Tuncer, S. F., Akpinar, F., Kayikcioglu, F., Koc, S., Karakaya, J. 2016. Is a history of cesarean section a risk factor for abnormal uterine bleeding in patients with uterine leiomyoma? Saudi Medical Journal, 37(8):871–876.

Kolhe, S. 2018. Management of abnormal uterine bleeding-focus on ambulatory hysteroscopy. International Journal of Women’s Health, Volume 10:127–136.

Lethaby, A., Wise, M. R., Weterings, M. A. J., Rodriguez, M., Brown, J. 2019. Combined hormonal contraceptives for heavy menstrual bleeding. The Cochrane Database of Systematic Reviews, 2:CD000154.

Luo, X., Feng, H., Jiang, L., Chen, Q. 2016. Abnormal uterine bleeding induced by glucocorticoid treatment for pemphigus. Saudi Medical Journal, 37(9):1025–1028.

Pandey, H., Pant, H., Pant, P., Rizvi, G., Chufal, S. S. 2013. Histopathological correlation of adenomyosis and leiomyoma in hysterectomy specimens as the cause of abnormal uterine bleeding in women in different age groups in the Kumaon region: A retroprospective study. Journal of Midlife Health, 4(1):27.

Puri, K., Famuyide, A. O., Erwin, P. J., Stewart, E. A., Laughlin-Tommaso, S. K. 2014. Submucosal fibroids and the relation to heavy menstrual bleeding and anemia. American Journal of Obstetrics and Gynecology, 210(1):38. e1–38. e7.

Rani, V. R. S., Thomas, S. 2013a. Leiomyoma, a major cause of Abnormal Uterine Bleeding. Journal of Evolution of Medical and Dental Sciences, 2(16):2626–2630.

Rani, V. S., Thomas, S. 2013b. Leiomyoma, a major cause of abnormal uterine bleeding. Journal of Evolution of Medical and Dental Sciences, 2(16):2626– 2631.

Sinha, K., Gurung, P., Sinha, H. H., Bhadani, P. P. 2018. Study on abnormal uterine bleeding among adult women in a tertiary care hospital in Bihar, India. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 7(8):3136–3136.

Sun, Y., Wang, Y., Mao, L., Wen, J., Bai, W. 2018. Prevalence of abnormal uterine bleeding according to new International Federation of Gynecology and Obstetrics classification in Chinese women of reproductive age. Medicine, 97(31): e11457.

Vannuccini, S., Petraglia, F. 2019. Recent advances in understanding and managing adenomyosis. F1000Research, 8:283.