A case report on Staphylococcal Scalded Skin Syndrome in a 3 year old: Clinical diagnosis and management

Gayathri Sunil (1) , Meghana Vinod (2) , Neethu C M (3) , Jis Ann Maria (4) , Vinitha Prasad (5)
(1) Department of Pharmacy Practice, Amrita School of Pharmacy, Amrita VishwaVidyapeetham, Kochi-682041, Kerala, India, India ,
(2) Department of Pharmacy Practice, Amrita School of Pharmacy, Amrita VishwaVidyapeetham, Kochi-682041, Kerala, India, India ,
(3) Department of Pharmacy Practice, Amrita School of Pharmacy, Amrita VishwaVidyapeetham, Kochi-682041, Kerala, India, India ,
(4) Department of Paediatrics, Amrita Institute Of Medical Sciences, Amrita VishwaVidyapeetham, Kochi-682041, Kerala, India, India ,
(5) Department of Paediatrics, Amrita Institute Of Medical Sciences, Amrita VishwaVidyapeetham, Kochi-682041, Kerala, India, India

Abstract

Staphylococcal-scalded skin syndrome (SSSS) is a blistering skin disorder which is considered as a pediatric emergency. This life-threatening syndrome is caused by Staphylococcal exfoliative toxins produced by Staphylococcus aureus. Although it can affect any age group, children below 5 years of age are at utmost risk. The specific antibodies to exotoxins and increased exotoxin clearance, minimize the frequency of SSSS in adults. Mortality in infancy is low (4%) and is less than 10 % in children but is between 40% and 63% in adults.  Clinical features of SSSS may range from a few localized blisters  to generalized desquamation covering the entire body. The histopathological evaluation of the skin biopsy helps in the definitive diagnosis of SSSS. Here we present a case of a 3 year old female child with low grade fever associated with erythematous rashes all over the body and severe itching. A clinical diagnosis of Staphylococcal Scalded Skin Syndrome (SSSS) was made. With appropriate treatment using intravenous Flucloxacillin and supportive care, the child’s symptoms were completely resolved within a week.

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Authors

Gayathri Sunil
Meghana Vinod
Neethu C M
Neethucm92@gmail.com (Primary Contact)
Jis Ann Maria
Vinitha Prasad
Gayathri Sunil, Meghana Vinod, Neethu C M, Jis Ann Maria, & Vinitha Prasad. (2020). A case report on Staphylococcal Scalded Skin Syndrome in a 3 year old: Clinical diagnosis and management. International Journal of Research in Pharmaceutical Sciences, 11((SPL 4), 1210–1212. Retrieved from https://ijrps.com/home/article/view/2056

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