The outcome of natural honey used in chronic ulcers

Nizam Ahmed (1) , Aftab Alam Khanzada (2) , Muhammad Rafique Joyo (3) , Tanveer Afzal (4) , Niaz Hussain Keerio (5) , Ghazanfar Ali Shah (6) , Syed Shahid Noor (7)
(1) Liaquat University of Medical and Health Science, Jamshoro, Pakistan, Pakistan ,
(2) Red Crescent General Hospital, Hyderabad, Pakistan, Pakistan ,
(3) Bone Care Trauma Centre, Hirabad Hospital, Hyderabad, Pakistan, Pakistan ,
(4) Ameer-ud-Din Medical College, Lahore General Hospital, Lahore, Pakistan, Pakistan ,
(5) Muhammad Medical College and Hospital, Mirpurkhas, Pakistan, Pakistan ,
(6) SMBBIT, Dow University of Medical and Health Sciences, Karachi, Pakistan, Pakistan ,
(7) Liaquat National Hospital and Medical College, Karachi, Pakistan, Pakistan

Abstract

The unique characteristics of natural honey obtained in any source in topical chronic nonhealing ulcers have been decreased discomfort, oedema, inflammation, deodorization, disinfect, neo-vascularization, collagen synthesis, granulation, epithelization and hence the ulcer treatment method. In that study, 200 patients were treated in a forward-looking, unrandomized experiment, with persistent, unhealing ulcers found in various areas of their body in the two groups keeping 100 in Group A and used honey dressing and Group B managed without using honey. Natural honey from multiple sources has been used. The main explanation for reduced mobility and loss of work illustrates productivity being pain and fever. The leading causes of healing delays were bacterial infection, necrotic tissue involvement, bedridden state, age, fatigue, Ulcer located near the joint. The quality, the simplicity of application and the efficiency make the control of recurrent nonhealing Ulcers easier for natural honey. For low cost, easy access, and improved healing make it a valuable option for natural honey to handle chronic, nonhealing ulcers, as well as healthy use in diabetic patients.

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References

Agbara, R., Obiadazie, A. C., Fomete, B., Omeje, K. U. 2016. Orofacial Soft Tissue Reconstruction with Locoregional Flaps in a Health Resource-Depleted Environment: Experiences from Nigeria. Archives of Plastic Surgery, 43:265–271.

Apriceno, A., Bucci, R., Girelli, A. M., Marini, F., Quattrocchi, L. 2018. 5-Hydroxymethyl furfural determination in Italian honeys by a fast near infrared spectroscopy. Microchemical Journal, 143:140–144.

Belay, A., Haki, G. D., Birringer, M., Borck, H., Lee, Y.-C., Kim, K.-T., Baye, K., Melaku, S. 2017. Enzyme activity, amino acid profiles and hydroxymethylfurfural content in Ethiopian monofloral honey. Journal of Food Science and Technology, 54(9):2769–2778.

Bhattacharya, S., Mishra, R. K. 2015. Pressure ulcers: current understanding and newer modalities of treatment. Indian journal of plastic surgery: official publication of the Association of Plastic Surgeons of India. Association of Plastic Surgeons of India, 48.

Bogdanov, S., Jurendic, T., Sieber, R., Gallmann, P. 2008. Honey for Nutrition and Health: A Review. Journal of the American College of Nutrition, 27:677–689.

Borsato, D. M., Prudente, A. S., Döll-Boscardin, P. M., Borsato, A. V., Luz, C. F. P., Maia, B. H. L. N. S., Cabrini, D. A., Otuki, M. F., Miguel, M. D., Farago, P. V., Miguel, O. G. 2014. Topical Anti-Inflammatory Activity of a Monofloral Honey of Mimosa scabrella Provided by Melipona marginata During Winter in Southern Brazil. Journal of Medicinal Food, 17(7):817–825.

Chua, L. S., Adnan, N. A. 2014. Biochemical and nutritional components of selected honey samples. Acta Scientiarum Polonorum Technologia Alimentaria, 13:169–179.

da Silva, P. M., Gauche, C., Gonzaga, L. V., Costa, A. C. O., Fett, R. 2016. Honey: Chemical composition, stability and authenticity. Food Chemistry, 196:309–323.

Erejuwa, O. O., Sulaiman, S. A., Wahab, M. S. A. 2012. Honey: A Novel Antioxidant. Molecules, 17(4):4400–4423.

Eteraf-Oskouei, T., Najafi, M. 2013. Traditional and modern uses of natural honey in human diseases: a review. Iranian journal of basic medical sciences, 16:731–742.

Hu, Z., Qu, S., Zhang, J., Cao, X., Wang, P., Huang, S., Shi, F., Dong, Y., Wu, J., Tang, B., Zhu, J. 2019. Efficacy and safety of platelet-rich plasma for patients with diabetic ulcers: a systematic review and meta-analysis. Advances in wound care, 8:298–308.

Mandal, M. D., Mandal, S. 2011. Honey: its medicinal property and antibacterial activity. Asian Pacific journal of tropical biomedicine, 1:154–60.

Martí-Carvajal, A. J., Gluud, C., Nicola, S., Simancas-Racines, D., Reveiz, L., Oliva, P., Cedeño-Taborda, J. 2015. Growth factors for treating diabetic foot ulcers. Cochrane Database of Systematic Reviews, (10):28.

Mcbride, C. A., Patel, B., Stockton, K. A., Kapoor, V., Kimble, R. M. 2018. Alginate dressings for donor sites of split-thickness skin grafts. The Cochrane Database of Systematic Reviews, 2018(6). CD013048.

Molan, P. C. 2002. Re-introducing honey in the management of wounds and ulcers-theory and practice. Ostomy/Wound management, pages 28–40.

Molan, P. C., Rhodes, T. 2015. Honey: A biologic wound dressing. Wounds: A compendium of clinical research and practice, pages 141–151.

Oryan, A., Alemzadeh, E., Moshiri, A. 2016. Biological properties and therapeutic activities of honey in wound healing: A narrative review and meta- analysis. Journal of Tissue Viability, 25(2):98–118.

Roecken, F. 2013. Honey in modern wound treatment-the renaissance of an ancient remedy. Kleintierpraxis, 58:617.

Shai, A., Halevy, S. 2005. Direct triggers for ulceration in patients with venous insufficiency. International Journal of Dermatology, 44(12):1006–1009.

Sherlock, O., Dolan, A., Athman, R., Power, A., Gethin, G., Cowman, S., Humphreys, H. 2010. Comparison of the antimicrobial activity of Ulmo honey from Chile and Manuka honey against methicillin-resistant Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. BMC Complementary and Alternative Medicine, 10:1–5.

Surahio, A. R., Khan, A. A., Farooq, M. U., I, F. 2014. Role of honey in wound dressing in diabetic foot ulcer. Journal of Ayub Medical College Abbottabad, 26(3):304–310.

Authors

Nizam Ahmed
Aftab Alam Khanzada
Muhammad Rafique Joyo
Tanveer Afzal
Niaz Hussain Keerio
niaz_h@hotmail.com (Primary Contact)
Ghazanfar Ali Shah
Syed Shahid Noor
Nizam Ahmed, Aftab Alam Khanzada, Muhammad Rafique Joyo, Tanveer Afzal, Niaz Hussain Keerio, Ghazanfar Ali Shah, & Syed Shahid Noor. (2021). The outcome of natural honey used in chronic ulcers. International Journal of Research in Pharmaceutical Sciences, 12(3), 1984–1989. Retrieved from https://ijrps.com/home/article/view/158

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