Determination of transverse diameter and longitudinal axis in patients with cholecystitis and cholelithiasis by computed tomography to rule out gallbladder carcinoma

Abstract

The aim of the article is to the determination of transverse diameter and longitudinal axis in patients with cholecystitis and cholelithiasis with the help of CT scan in the north Indian population for the estimation of epidemiology. Patients with cholecystitis and cholelithiasis of ages between 17-80 years irrespective of gender were included in the study (cases). All patient's cases (100) and controls (100) were advised the night before that did not eat or drink. Control groups (Normal Gallbladder) were collected when patients are comprised of other abdominal disease diagnosed by computed tomography. The mean age of controls and cases was 47.24±11.57 and 45.20±16.22 years, respectively studied by computed tomography. More than half of cases (62%) and 50% of controls were females. The transverse diameter was significantly (p=0.0001) higher among cases (36.42±15.52 mm) than controls (24.12±9.11 mm) studied by computed tomography. Longitudinal axis was significantly (p=0.0001) higher among cases (33.23±14.73 mm) than controls (21.75±8.69) studied by computed tomography. Transverse diameter>25 correctly predicted cholecystitis and cholelithiasis by CT in 38.5% cases with sensitivity and specificity of 77% (95%CI=68.8-85.2) and 74% (95%CI=55.7-74.3%) respectively. Longitudinal axis >25 correctly predicted cholecystitis and cholelithiasis by CT in 34.5% cases with specificity and sensitivity of 69% (95%CI=59.9-78.1) and 71% (95%CI=62.1-79.9%) respectively. We concluded in this study, increased transverse diameter and longitudinal axis were observed. Good sensitivity and specificity of these two parameters were also found in predicting cholecystitis and cholelithiasis by computed tomography.