Cynodon dactylon Mediated Synthesis of Selenium Nanoparticles and Its Antimicrobial Activity Against Oral Pathogens

Akansha Kishen (1) , Rajeshkumar S (2) , Preejitha V. B. (3)
(1) Department of Pathology, Saveetha Dental College and Hospital, SIMATS, Chennai – 600077, Tamilnadu, India, India ,
(2) Nanobiomedicine Lab, Department of Pharmacology, Saveetha Dental College and Hospital, SIMATS, Chennai – 600077, Tamilnadu, India, India ,
(3) Department of Pathology, Saveetha Dental College and Hospital, SIMATS, Chennai – 600077, Tamilnadu, India, India

Abstract

Cynodon is a genus of plant in the grass family. It is found in the tropical regions and is also known as druva grass, Bermuda grass and Indian Doab.  It is a herb extensively used in Indian Ayurvedic system of medicine. It has many health benefits and is useful in controlling hypertension, skin diseases and diabetes. Selenium nano particles have an excellent anti-cancer, biocidal, antioxidant, photo reactive property. The size of SeNPs ranges from 30nm  to 200 nm. These particles can be used in arthritis, cancer, diabetes etc. To prepare the selenium nano particles using Cynodon dactylon, fresh Cynodon dactylon was dried and made into a fine powder and powder mixed with distilled water. Selenium nanoparticles were synthesized using plant extract and sodium selenite. Anti microbial activity against oral pathogens tested using agar well diffusion method. The diameter of zone of inhibition was recorded on each plate. The colour change was indicative of the formation of SeNPs that was further confirmed by UV-vis spectrophotometer. The Cynodon dactylon mediated SeNPs showed high anti microbial activity against all the three micro-organisms especially Candida albicans and S.mutans. Therefore, diseases can be prevented as it is very effective in inhibiting the growth of the colonies.

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Authors

Akansha Kishen
Rajeshkumar S
ssrajeshkumar@hotmail.com (Primary Contact)
Preejitha V. B.
Akansha Kishen, Rajeshkumar S, & Preejitha V. B. (2020). Cynodon dactylon Mediated Synthesis of Selenium Nanoparticles and Its Antimicrobial Activity Against Oral Pathogens. International Journal of Research in Pharmaceutical Sciences, 11(3), 4152–4156. Retrieved from https://ijrps.com/home/article/view/1010

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