Comparison of intravenous ibuprofen and intravenous ketorolac effectivity for non-specific acute musculoskeletal pain

Rizaldy Taslim Pinzon (1) , Tifany Edfa Susanto (2)
(1) Department of Neurology, Faculty of Medicine, Duta Wacana Christian University, Wahidin Sudirohusodo street number 5-25, Yogyakarta 55224, Indonesia, India ,
(2) Department of Neurology, Faculty of Medicine, Duta Wacana Christian University, Wahidin Sudirohusodo street number 5-25, Yogyakarta 55224, Indonesia, India

Abstract

Acute musculoskeletal pain is an illness of muscle, bone, joint, and muscle tissue that is caused by an injury or inflammation. Ibuprofen and Ketorolac are Non-Steroid Anti-Inflammatory Drugs or NSAID that are usually used for non-specific acute musculoskeletal pain. The purpose of the study is to compare the pain relief of non-specific acute musculoskeletal pain between intravenous Ibuprofen and intravenous Ketorolac therapy. This study uses a quasi-experimental, non-randomized, non-equivalent, active comparator, open-label study. The total sample for this study is 60 subjects, divided into two groups (n-30), subjects are required by using purposive sampling. Pain measured by Numeric Pain Scale. The mean baseline of the pain intensity were 63.33 ± 8.841 for the Ibuprofen group and 59.33 ± 12.847 for the Ketorolac group. There was not any differences between both of group (p = 0.107) after the medication were given all measurement shows significant differences between two groups (p = <0.05) that Ibuprofen group shows better results. Intravenous Ibuprofen has better effectivity rather than intravenous Ketorolac as a treatment of non-specific acute musculoskeletal pain.

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Authors

Rizaldy Taslim Pinzon
drpinzon17@gmail.com (Primary Contact)
Tifany Edfa Susanto
Rizaldy Taslim Pinzon, & Tifany Edfa Susanto. (2021). Comparison of intravenous ibuprofen and intravenous ketorolac effectivity for non-specific acute musculoskeletal pain. International Journal of Research in Pharmaceutical Sciences, 12(3), 1788–1792. Retrieved from https://ijrps.com/home/article/view/85

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