Preparation, Characterization and Stability Study of Oral Reconstitutable Suspension of Amoxicillin and Potassium Clavulanate
To overcome the problem of bitter taste, degradation, and sedimentation, reconstitutable suspension of Amoxicillin and Potassium Clavulanate was prepared. The suspension was prepared by using two different formulations. The suspensions were characterized for micromeritic studies such as bulk density, tap density, Car’s index, angle of repose, pH, and viscosity. The HPLC assay was performed for the quantitative determination of Amoxicillin and Clavulanate potassium from suspension. The accelerated stability study was carried out to predict the stability profile of a drug product. Formulated reconstitutable suspension of Amoxicillin and Potassium Clavulanate has IPQC properties. From the results, it is concluded that reconstitutable suspension was successfully prepared and evaluated.
Keywords:Reconstitutable, Micromeritic, Carr’s Index, HPLC Assay, Accelerated Stability
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