Determination of Total Phenolic Content and Antioxidant Activity of the Whole Plant Extracts of Argyreia imbricata (Roth) Sant. & Patel

Sebastin V (1) , Gopalakrishnan G (2) , Sreejith M (3) , Anoob Kumar K I (4)
(1) Department of Pharmaceutical Chemistry, Malik Deenar College of Pharmacy, Seethangoli, Kasaragod, Kerala, India, India ,
(2) Department of Pharmacy, Annamalai University, Annamalai Nagar, Chidambaram, Tamil Nadu, India , India ,
(3) Department of Pharmaceutical Chemistry, Nazareth College of Pharmacy, Thiruvalla, Pathanamthitta, Kerala, India, India ,
(4) Department of Pharmaceutical Chemistry, KVM College of Pharmacy, Cherthala, Alappuzha, Kerala, India, India

Abstract

Plants of the genus Argyreia posses’ ethno medicinal importance and various pharmacological activities are also reported. In this study, phenolic content, anti-oxidant potential of different extracts of Argyreia imbricata was evaluated. Extraction of powdered whole plant material was done with different solvents viz., petroleum ether, chloroform, ethyl acetate and methanol by soxhelation. The estimation of phenolics in the selected extracts of Argyreia imbricata was done by using a Folin-Ciocalteau reagent. The antioxidant potential of different extracts was evaluated by total anti-oxidant capacity, DPPH, hydroxyl and nitric oxide radical scavenging and reducing power assay methods. In the phenolics estimation, the methanol extract showed a significant presence of phenolic content followed by ethyl acetate extract. In case of anti-oxidant activity, the methanol and ethyl acetate extract showed a significant activity based on their concentration. The findings of this study clearly revealed the potential of methanol extract of A. imbricata in phenolic content and anti-oxidant activity. Also, the ethyl acetate extract showed significant results. Further studies on identification, isolation of the active constituents, toxicity evaluations may give useful results.

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Authors

Sebastin V
seba.pharm@gmail.com (Primary Contact)
Gopalakrishnan G
Sreejith M
Anoob Kumar K I
Sebastin V, Gopalakrishnan G, Sreejith M, & Anoob Kumar K I. (2021). Determination of Total Phenolic Content and Antioxidant Activity of the Whole Plant Extracts of Argyreia imbricata (Roth) Sant. & Patel. International Journal of Research in Pharmaceutical Sciences, 12(1), 919–925. Retrieved from https://ijrps.com/home/article/view/441

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