A successful RH ISO immunization in pregnancy and perinatal outcome

Hepsibah Kirubamani (1) , Pavithra Baskaran (2) , Nasreen Banu M. (3)
(1) Department of Obstetrics and Gynaecology, Saveetha Medical College and Hospital, Chennai, Tamil Nadu, India, India ,
(2) Department of Obstetrics and Gynaecology, Saveetha Medical College and Hospital, Chennai, Tamil Nadu, India, India ,
(3) Department of Obstetrics and Gynaecology, Saveetha Medical College and Hospital, Chennai, Tamil Nadu, India, India

Abstract

RH ISO immunization is a major cause of severe hemolytic Anemia in newborns and poor perinatal outcomes. Nowadays, the rate of isoimmunization is rising so careful monitoring and follow up is required in the mother to improve the perinatal mortality. A case of multigravida, Rh iso immunized with titre value of 1:8 ago; this case defines how the perinatal outcome with this level of titre value and the events of a baby after immediate delivery. Rh isoimmunization is diagnosed with Doppler ultrasound to calculate the MOM VALUE, if >1.5, then it needs an immediate termination, exchange transfusion, IVIG and double light phototherapy are the options in the treatment in Fetal Anemia. Advantages of IVIG use before transfusion case reports show a reduction in the transfusion rate and phototherapy. This case report showed the successful RH isoimmunization in pregnancy with an ICT titre of 1:8 and the related perinatal outcome. PSV AND MSV Doppler which is a noninvasive test which is used to benefit the Rh isoimmunization patient; however, if the mom is within normal limits, we can be able to prolong the pregnancy, or we might know when the ideal time is to terminate the pregnancy along with Doppler nowadays if titre of more than 1:32, IVIG is also one good option to eliminate the repeated exchange transfusions and phototherapy for the baby.

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Authors

Hepsibah Kirubamani
Pavithra Baskaran
pavikanci2016@gmail.com (Primary Contact)
Nasreen Banu M.
Hepsibah Kirubamani, Pavithra Baskaran, & Nasreen Banu M. (2022). A successful RH ISO immunization in pregnancy and perinatal outcome. International Journal of Research in Pharmaceutical Sciences, 13(2), 218–221. https://doi.org/10.26452/ijrps.v13i2.342

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