A comprehensive review of the traditional plant based medicines for the treatment of rheumatism

Ganesh N Sharma (1) , Harjinder Kaur (2) , Birendra Shrivastava (3) , Satish Chander Arora (4)
(1) Department of Pharmacology, School of Pharmaceutical Sciences, Jaipur National University, Jaipur-302017, Rajashthan, India, India ,
(2) Department of Pharmacology, School of Pharmaceutical Sciences, Jaipur National University, Jaipur-302017, Rajashthan, India, India ,
(3) Department of Pharmachemistry, School of Pharmaceutical Sciences, Jaipur National University, Jaipur -302017, Rajasthan, India, India ,
(4) Department of Pharmaceutics, RKSD College of Pharmacy, Kaithal-136027, Haryana, India, India

Abstract

Inflammation is a highly complex mechanism and can be described as the body’s first defensive immune system reaction. The immediate purpose is to guard against infectious invasions, the introduction of antigens, any cell and tissue disruption or harm. If it is not treated, it is persistent which progresses to serious degenerative conditions such as rheumatism, atherosclerosis and asthma. Rheumatism is a category of inflammatory disease with chronic conditions. The disease includes a rise in the amount of neutrophils, lymphocytes and monocytes, which primarily influence the synovial fluid of the movable joints and eventually cause cartilage and bone degradation across the joints. Many steroidal and nonsteroidal drugs (Methotrexate, Cyclosporine and Dpencillamine, Ibuprofen, Sulindac, Indomethacin) are prescribed as treatment therapies. But, unfortunately, all these drugs are having side effects. So, to enhance the pharmacological effects and decrease the side-effects of the available treatment therapies, there is a need to move towards alternative therapies. By keeping the limitations of the existing therapies, in the present review, we tried to summarize the data of traditional medicinal plants with maximum pharmacological activities with less side effects for the rheumatism patients. A systematic literature and electronic archive analysis was performed using internet search engines such as Google scholar, Pubmed, Medlineplus, and Science Direct from numerous academic publications. This review paper is summarized with total 500 articles out of which 330 articles are selected to review for extracts and parts used, chemical constituents, traditional uses and for reporting anti rheumatic activity.

Full text article

Generated from XML file

References

Aleti, S., Reddy, M. S., Sneha, J. A., Suvarchala, N. V. L. 2015. Wound Healing Activity of Mimusops elengi Leaves. Iranian Journal of Pharmacology and Therapeutics, 13(1):13–13.

Ammon, H. P., Muller, B. A. 1985. Forskolin: from an Ayurvedic remedy to a modern agent. Planta Med, 51(6):473–477.

Asdaq, S. M. B., Rao, G. S., Ananth, K. V., Asad, M., Kumar, N. P. 2010. Evaluation of wound healing potential ofbauhinia purpurealeaf extracts in rats. Indian Journal of Pharmaceutical Sciences, 72(1):122–122.

Asif, M., Kumar, A. 2011. Phytochemical investigation and evaluation of antinociceptive activity of ethanolic extract of Dalbergia sissoo (Roxb.) bark. Journal of Natural Science, Biology and Medicine, 2(1):76–76.

Babushetty, V., Sultanpur, M. C. 2012. Evaluation of anti-arthritis activity of Asystasia dalzelliana leaves. Int J Pharma Biol Arch, 3(2):377–382.

Bah, S., Jäger, A. K., Adsersen, A., Diallo, D., Paulsen, B. S. 2007. Antiplasmodial and GABAA– benzodiazepine receptor binding activities of five plants used in traditional medicine in Mali, West Africa. Journal of Ethnopharmacology, 110(3):451–457.

Bhanumathy, M., Harish, M. S., Shivaprasad, H. N., Sushma, G. 2010. Nootropic activity of Celastrus paniculatus seed. Pharmaceutical Biology, 48(3):324–327.

Bhujade, A., Talmale, S. 2015. In vivo Studies on Antiarthritic Activity of Cissus quadrangularis against Adjuvant Induced Arthritis. Journal of Clinical & Cellular Immunology, 06(03):100027– 100034.

Eggadi, V., Pashikanti, G., Kulundaivelu, U., Jupalli, V., Sheshagiri, S. B. 2014. Anti-arthritic activity of ethanolic extract from the leaves of Commiphora caudata (Linn.) in complete Freund′s adjuvant induced arthritic rats. Nigerian Journal of Experimental and Clinical Biosciences, 2(1):42–42.

Fujita, E., Ochiai, M., Ichida, I., Chatterjee, A., Deshmukh, S. K. 1950. Confirmation of the structure of calliterpenone, a diterpene from Callicarpa macrophylla Vahl. Phytochemistry, 4:568–568.

Gabriel, S. E., Crowson, C. S., Kremers, H. M., Doran, M. F., Turesson, C., O’Fallon, W. M., Matteson, E. L. 2003. Survival in rheumatoid arthritis: A population-based analysis of trends over 40 years. Arthritis & Rheumatism, 48(1):54–58.

Gamlath, C. B., Gunatilaka, A. A. L., Tezuka, Y., Kikuchi, T., Balasubramaniam, S. 1990. Quinone methide, phenolic and related triterpenoids of plants of Celastraceae: further evidence for the structure ofCelastranhydride. Phytochemistry, 29(10):3189–3192.

Gatinode, B. B., Raiker, K. P., Shroff, F. N., Patel, J. R. 1957. Pharmacological studies with malkanguni, an indigenous tranquilizing drug (preliminary report). Current Practice, 1:619–621.

Jain, S., Kohli, S. 2015. Isolation and evaluation of chemical constituents of Cissus quadrangularis. Natural Product Chemistry and Research, pages 5– 8.

Khatri, D. K., Manjulakonka, Juvekar, A. R. 2014. Evaluation of anti-inflammatory activity of Mimusops elengi extracts in different in vitro and in vivo models. Int J Pharm Biol Sci, 5(3):259–268.

Koti, B. C., Thippeswamy, A. H. M., Jaji, M. S., Swamy, A. H. M., Kurhe, Y. V., Sadiq, A., Purnima, A. 2010. Antiinflammatory, analgesic and antipyretic activities of Mimusops elengi Linn. Indian Journal of Pharmaceutical Sciences, 72(4):480–480.

Menon, D. B., Latha, K. 2011. Phytochemical Screening and In vitro Anti-inflammatory Activity of the Stem of Coleus forskohlii. Pharmacognosy Journal, 3(23):75–79.

Mittal, S., Dixit, P. K. 2013. In vivo anti inflammatory and antiarthritic activity of Asparagus racemosus roots. International Journal of Pharmaceutical Sciences and Research, 4(7):2652–2658.

Patil, M. V. K., Kandhare, A. D., Bhise, S. D. 2012. Anti-arthritic and anti-inflammatory activity of Xanthium srtumarium L. ethanolic extract in Freund’s complete adjuvant induced arthritis. Biomedicine & Aging Pathology, 2(1):6–15.

Perumal, S. S., Ekambaram, S. P., Dhanam, T. 2017. In vivo antiarthritic activity of the ethanol extracts of stem bark and seeds of Calophyllum inophyllum in Freund’s complete adjuvant induced arthritis. Pharmaceutical Biology, 55(1):1330–1336.

Raja, R. R., Kailasam, K. V. 2015. Abutilon indicum L (Malvaceae)-Medicinal Potential Review. Pharmacognosy Journal, 7(6):330–332.

Sankara, S., Nair, A. G. R. 1972. Flavonoids of four malveceous plants. Phytochemistry, 11:1518– 1519.

Saraswathi, R., Upadhyay, L., Venkatakrishnan, R., Meera, R., Devi, P. 2011. Phytochemical investigation, analgesic and anti inflammatory activity of Abutilon indicum Linn. Int J Pharm Pharm Sci, 3(2):154–156.

Shreedhara, C. S., Vaidya, V. P., Vagdevi, H. M., Latha, K. P., Muralikrishna, K. S., Krupanidhi, A. M. 2009. Screening of Bauhinia purpurea Linn. for analgesic and anti-inflammatory activities. Indian Journal of Pharmacology, 41(2):75–75.

Sidhana, J. K., Saini, V., Dahiya, S. 2012. Analgesic and anti-inflammatory activities of Dalbergia sissoo leaves extract. International Journal of Natural Product Science, 1:134–134.

Srivastava, S., Singh, P., Keshri, K., Mishra, G., Srivatava, S., Ratan, L. K. 2012. Evaluation of anti- arthritic potential of the methanolic extract of the aerial parts of Costus speciosus. Journal of Ayurveda and Integrative Medicine, 3(4):204–208.

Sunil, K., Kumar, R., Gupta, Y. K., Singh, S. 2019. In vivo antiarthritic activity of Bauhinia purpurea Linn. bark extract. Indian Journal of Pharmacology, pages 51–51.

Tandon, V., Gupta, R. K. 2004. Histomorphological changes induced by Vitex negundo in albino rats. Indian journal of pharmacology, 36(3):176–177.

Tripathi, P., Chauhan, N. S., Patel, J. R. 2012. Anti- inflammatory activity ofAbutilon indicumextract. Natural Product Research, 26(17):1659–1661.

Wassel, M., Abdel-Wahab, S. M., Ammar, N. M. 1986. Constituents of the essential oils from Bauhinia variegate and Bauhinia purpurea L. flowers. Scientia Pharmaceutica, 54:357–361.

Zakaria, M. B., Vijayasekarana, Z. I., Muhammad, N. A. 2014. Anti-inflammatory activity of Calophyllum inophyllum fruit extracts. Procedia Chemistry, 13:218–220.

Zakaria, Z. A., Hisam, E. E. A., Norhafizah, M., Rofiee, M. S., Othman, F., Hasiah, A. H., Vasudevan, M. 2012. Methanol Extract of Bauhinia purpurea Leaf Possesses Anti-Ulcer Activity. Medical Principles and Practice, 21(5):476–482.

Authors

Ganesh N Sharma
Harjinder Kaur
ysdverma@gmail.com (Primary Contact)
Birendra Shrivastava
Satish Chander Arora
Ganesh N Sharma, Harjinder Kaur, Birendra Shrivastava, & Satish Chander Arora. (2021). A comprehensive review of the traditional plant based medicines for the treatment of rheumatism. International Journal of Research in Pharmaceutical Sciences, 12(1), 576–587. Retrieved from https://ijrps.com/home/article/view/297

Article Details

Most read articles by the same author(s)

1 2 > >> 
No Related Submission Found